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基于依恋的共情疗法(ABCT)治疗纤维肌痛与放松疗法相比的成本效益:一项随机对照试验试点研究

Cost-Utility of Attachment-Based Compassion Therapy (ABCT) for Fibromyalgia Compared to Relaxation: A Pilot Randomized Controlled Trial.

作者信息

D'Amico Francesco, Feliu-Soler Albert, Montero-Marín Jesús, Peñarrubía-María María T, Navarro-Gil Mayte, Van Gordon William, García-Campayo Javier, Luciano Juan V

机构信息

Personal Social Services Research Unit, London School of Economics and Political Science, London WC2A 2AE, UK.

Institut de Recerca Sant Joan de Déu, 08950 Esplugues de Llobregat, Spain.

出版信息

J Clin Med. 2020 Mar 7;9(3):726. doi: 10.3390/jcm9030726.

Abstract

A recent study has supported the efficacy of Attachment-Based Compassion Therapy (ABCT) compared to relaxation (REL) for the management of fibromyalgia (FM). The main objective of this paper is to examine the cost-utility of ABCT compared to REL in terms of effects on quality-adjusted life years (QALYs) as well as healthcare costs. Forty-two Spanish patients with FM received 8 weekly group sessions of ABCT or REL. Data collection took place at pre- and 3-month follow-up. Cost-utility of the two treatment groups (ABCT vs. REL) was compared by examining treatment outcomes in terms of QALYs (obtained with the EQ-5D-3L) and healthcare costs (data about service use obtained with the Client Service Receipt Inventory). Data analyses were computed from a completers, ITT, and per protocol approach. Data analysis from the healthcare perspective revealed that those patients receiving ABCT exhibited larger improvements in quality of life than those doing relaxation, while being less costly 3 months after their 8-week treatment program had ended (completers: incremental cost M, 95% CI = €-194.1 (-450.3 to 356.1); incremental effect M, 95% CI = 0.023 QALYs (0.010 to 0.141)). Results were similar using an ITT approach (incremental cost M, 95% CI = €-256.3 (-447.4 to -65.3); incremental effect M, 95% CI = 0.021 QALYs (0.009 to 0.033)). A similar pattern of results were obtained from the per protocol approach. This RCT has contributed to the evidence base of compassion-based interventions and provided useful information about the cost-utility of ABCT for FM patients when compared to relaxation. However, the small sample size and short follow-up period limited the generalizability of the findings.

摘要

最近一项研究证实,与放松疗法(REL)相比,基于依恋的同情疗法(ABCT)在纤维肌痛(FM)管理方面具有疗效。本文的主要目的是,就对质量调整生命年(QALY)的影响以及医疗成本而言,研究ABCT与REL相比的成本效益。42名西班牙FM患者接受了为期8周的ABCT或REL每周一次的团体治疗。在治疗前和3个月随访时进行数据收集。通过检查QALY(使用EQ-5D-3L获得)和医疗成本(使用客户服务收据清单获得的服务使用数据)方面的治疗结果,比较两个治疗组(ABCT与REL)的成本效益。数据分析采用完成者分析、意向性分析和符合方案分析方法。从医疗保健角度进行的数据分析显示,接受ABCT治疗的患者在生活质量方面的改善比接受放松疗法的患者更大,并且在为期8周的治疗计划结束3个月后成本更低(完成者分析:增量成本M,95%置信区间=€-194.1(-450.3至356.1);增量效果M,95%置信区间=0.023 QALY(0.010至0.141))。采用意向性分析方法得出的结果相似(增量成本M,95%置信区间=€-256.3(-447.4至-65.3);增量效果M,95%置信区间=0.021 QALY(0.009至0.033))。从符合方案分析方法中也获得了类似的结果模式。这项随机对照试验为基于同情的干预措施的证据基础做出了贡献,并提供了与放松疗法相比ABCT对FM患者成本效益的有用信息。然而,样本量小和随访期短限制了研究结果的普遍性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c515/7141201/800ff633451e/jcm-09-00726-g001.jpg

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