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正念减压疗法和基于依恋的慈悲疗法对心理健康环境中抑郁、焦虑和适应障碍的治疗效果:一项随机对照试验。

Effectiveness of mindfulness-based stress reduction and attachment-based compassion therapy for the treatment of depressive, anxious, and adjustment disorders in mental health settings: A randomized controlled trial.

机构信息

Department of Psychology, University and Polytechnic La Fe Hospital, Valencia, Spain.

Department of Psychology and Sociology, Department of Psychiatry, University of Zaragoza, Zaragoza, Spain.

出版信息

Depress Anxiety. 2021 Nov;38(11):1138-1151. doi: 10.1002/da.23198. Epub 2021 Jul 20.

DOI:10.1002/da.23198
PMID:34288280
Abstract

OBJECTIVES

To study the effectiveness of attachment-based compassion therapy (ABCT) for reducing affective distress in a sample of outpatients with depressive, anxiety, or adjustment disorders, and to explore its mechanisms of action.

METHODS

This randomized controlled trial involved the assessment time points of pretreatment, posttreatment and 6-month follow-up. A total of 90 patients from three mental health units in Castellón, Spain, were recruited and randomly assigned to "ABCT + treatment as usual (TAU)," "Mindfulness-based stress reduction (MBSR) + TAU" or "TAU" alone. Affective distress, as measured by the "Depression, Anxiety and Stress Scales" (DASS-21) was the main outcome; self-compassion and mindfulness were also assessed. Multilevel mixed-effects models were used to estimate the effectiveness of the program, and path analyses were conducted to study the potential mechanistic role of mindfulness and self-compassion.

RESULTS

ABCT was not superior to MBSR in any outcome or at any assessment point. ABCT was superior to TAU alone both posttreatment (B = -13.20; 95% confidence interval [CI]: -19.57, -6.84) and at 6-month follow-up (B = -7.20; 95% CI: -13.63, -0.76) for reducing DASS-21, and MBSR was superior to TAU alone both posttreatment (B = -11.51; 95% CI: -17.97, -5.05) and at 6-month follow-up (B = -8.59; 95% CI: -15.09, -2.10), with large effects (d ≥ 0.90). Changes produced by ABCT in DASS-21 were mediated by self-compassion, whereas changes produced by MBSR were mediated by both mindfulness and self-compassion.

CONCLUSION

ABCT is effective for reducing affective distress in patients with anxiety, depressive and adjustment disorders, although its effect is not superior to that offered by MBSR. Self-compassion seems to be a significant mediator of the effects of ABCT.

摘要

目的

研究基于依恋的同情治疗(ABCT)在减少抑郁、焦虑或适应障碍门诊患者情感困扰方面的有效性,并探讨其作用机制。

方法

这是一项随机对照试验,评估时间点包括治疗前、治疗后和 6 个月随访。共招募了来自西班牙卡斯特利翁的三个心理健康单位的 90 名患者,并随机分配到“ABCT+常规治疗(TAU)”、“正念减压(MBSR)+TAU”或“TAU”单独治疗组。主要结局为“抑郁、焦虑和压力量表”(DASS-21)评估的情感困扰;还评估了自我同情和正念。采用多层次混合效应模型估计该方案的有效性,并进行路径分析以研究正念和自我同情的潜在机制作用。

结果

ABCT 在任何结果或任何评估点上均不比 MBSR 更有效。ABCT 在治疗后(B=-13.20;95%置信区间[CI]:-19.57,-6.84)和 6 个月随访时(B=-7.20;95% CI:-13.63,-0.76)均优于 TAU 单独治疗,而 MBSR 在治疗后(B=-11.51;95% CI:-17.97,-5.05)和 6 个月随访时(B=-8.59;95% CI:-15.09,-2.10)均优于 TAU 单独治疗,效果较大(d≥0.90)。ABCT 对 DASS-21 的影响通过自我同情来介导,而 MBSR 对 DASS-21 的影响通过正念和自我同情来介导。

结论

ABCT 对减轻焦虑、抑郁和适应障碍患者的情感困扰有效,尽管其效果不如 MBSR。自我同情似乎是 ABCT 效果的重要中介。

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