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Pomegranate peel extract ameliorates the severity of experimental autoimmune encephalomyelitis via modulation of gut microbiota.石榴皮提取物通过调节肠道微生物群改善实验性自身免疫性脑脊髓炎的严重程度。
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The Role of Lactic Acid Bacteria in Improving Behavioral Deficits, Serum Levels of Vitamin D3, B12 and Reducing Oxidative Stress and Demyelination in a Cuprizone-induced Demyelination Model of Rat.乳酸菌在改善铜离子螯合剂诱导的大鼠脱髓鞘模型中的行为缺陷、血清维生素D3和B12水平以及减轻氧化应激和脱髓鞘方面的作用
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A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.饮食依赖性宿主代谢物塑造肠道微生物群,以防止自身免疫。
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Network analysis of gut microbial communities reveal key genera for a multiple sclerosis cohort with Mycobacterium avium subspecies paratuberculosis infection.肠道微生物群落的网络分析揭示了患有副结核分枝杆菌感染的多发性硬化症队列中的关键属。
Gut Pathog. 2024 Jul 10;16(1):37. doi: 10.1186/s13099-024-00627-7.
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Targeting gut microbiota: new therapeutic opportunities in multiple sclerosis.靶向肠道菌群:多发性硬化症的新治疗机会。
Gut Microbes. 2023 Dec;15(2):2274126. doi: 10.1080/19490976.2023.2274126. Epub 2023 Nov 18.
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Multiple Sclerosis-Associated Gut Microbiome in the Israeli Diverse Populations: Associations with Ethnicity, Gender, Disability Status, Vitamin D Levels, and Mediterranean Diet.以色列不同人群多发性硬化症相关的肠道微生物组:与种族、性别、残疾状况、维生素 D 水平和地中海饮食的关联。
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本文引用的文献

1
Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility.海鲜、脂肪酸生物合成基因与多发性硬化症易感性。
Mult Scler. 2020 Oct;26(12):1476-1485. doi: 10.1177/1352458519872652. Epub 2019 Sep 6.
2
Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism.丙酸通过免疫调节机制影响多发性硬化的病程。
Cell. 2020 Mar 19;180(6):1067-1080.e16. doi: 10.1016/j.cell.2020.02.035. Epub 2020 Mar 10.
3
Randomized-controlled trial of a modified Mediterranean dietary program for multiple sclerosis: A pilot study.随机对照试验研究改良地中海饮食方案对多发性硬化症的影响:一项初步研究。
Mult Scler Relat Disord. 2019 Nov;36:101403. doi: 10.1016/j.msard.2019.101403. Epub 2019 Sep 24.
4
Diet-microbiota interactions and personalized nutrition.饮食-微生物群相互作用与个性化营养。
Nat Rev Microbiol. 2019 Dec;17(12):742-753. doi: 10.1038/s41579-019-0256-8. Epub 2019 Sep 20.
5
Neuroimmunological characterization of a mouse model of primary progressive experimental autoimmune encephalomyelitis and effects of immunosuppressive or neuroprotective strategies on disease evolution.原发性进行性实验性自身免疫性脑脊髓炎小鼠模型的神经免疫特征及免疫抑制或神经保护策略对疾病演变的影响。
Exp Neurol. 2019 Dec;322:113065. doi: 10.1016/j.expneurol.2019.113065. Epub 2019 Sep 16.
6
Gut Microbiota Interventions With and Norfloxacin Modulate Immune Response in Experimental Autoimmune Encephalomyelitis Mice.肠道微生物群干预和诺氟沙星调节实验性自身免疫性脑脊髓炎小鼠的免疫反应。
Front Immunol. 2019 Jul 23;10:1662. doi: 10.3389/fimmu.2019.01662. eCollection 2019.
7
Butyrate suppresses demyelination and enhances remyelination.丁酸盐能抑制脱髓鞘并增强髓鞘再生。
J Neuroinflammation. 2019 Aug 9;16(1):165. doi: 10.1186/s12974-019-1552-y.
8
Influence of a 3-month low-calorie Mediterranean diet compared to the vegetarian diet on human gut microbiota and SCFA: the CARDIVEG Study.3 个月低热量地中海饮食与素食饮食对人体肠道微生物群和 SCFA 的影响:CARDIVEG 研究。
Eur J Nutr. 2020 Aug;59(5):2011-2024. doi: 10.1007/s00394-019-02050-0. Epub 2019 Jul 10.
9
The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells.肠道中存在具有不同功能的稳态组织驻留和炎症性 Th17 细胞。
Immunity. 2019 Jul 16;51(1):77-89.e6. doi: 10.1016/j.immuni.2019.05.004. Epub 2019 Jun 19.
10
Bidirectional regulatory potentials of short-chain fatty acids and their G-protein-coupled receptors in autoimmune neuroinflammation.短链脂肪酸及其 G 蛋白偶联受体在自身免疫性神经炎症中的双向调节作用。
Sci Rep. 2019 Jun 20;9(1):8837. doi: 10.1038/s41598-019-45311-y.

Role of diet in regulating the gut microbiota and multiple sclerosis.

作者信息

Sanchez John Michael S, DePaula-Silva Ana Beatriz, Libbey Jane E, Fujinami Robert S

机构信息

Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East, 2600 EEJMRB, Salt Lake City, UT 84112, USA.

Department of Pathology, University of Utah School of Medicine, 15 North Medical Drive East, 2600 EEJMRB, Salt Lake City, UT 84112, USA.

出版信息

Clin Immunol. 2022 Feb;235:108379. doi: 10.1016/j.clim.2020.108379. Epub 2020 Mar 7.

DOI:10.1016/j.clim.2020.108379
PMID:32156562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7483914/
Abstract
摘要