Acta Derm Venereol. 2020 Apr 29;100(8):adv00125. doi: 10.2340/00015555-3447.
Paediatric lymphoedema (LE) is a rare condition, for which there is little data available regarding treatments. The aim of this study was to assess the short-term effect and acceptability of a 30-min session of manual lymphatic drainage (MLD) in children with well-documented LE of the lower limbs. Fifteen children were included (8 males; median age 11 years). Comparison of the sum of circumference values for the whole limb before and after MLD revealed a slight, but significant, reduction (from a median of 289.8 to 285.5 cm, p = 0.024), but the limb volumes did not decrease significantly (from a median of 4,870.3 to 4,772.3 ml, p = 0.394). Dermal thickness, measured by high-resolution ultrasound, decreased from 1.44 to 1.40 mm (p < 0.001). All children reported improvement in well-being, and found MLD useful. In conclusion, MLD is well accepted by children, but has poor impact on LE swelling. However, it decreases cutaneous oedema by mobilizing the lymph fluid.
儿科淋巴水肿（LE）是一种罕见的疾病，针对其治疗方法的数据很少。本研究旨在评估 30 分钟手动淋巴引流（MLD）对下肢明确诊断为 LE 的儿童的短期效果和可接受性。共纳入 15 名儿童（男性 8 名；中位年龄 11 岁）。MLD 前后整个肢体周长值的总和比较显示，虽然略有但具有统计学意义的减少（从中位数 289.8 厘米减少至 285.5 厘米，p=0.024），但肢体体积无明显减少（从中位数 4870.3 毫升减少至 4772.3 毫升，p=0.394）。通过高分辨率超声测量的真皮厚度从 1.44 毫米减少至 1.40 毫米（p<0.001）。所有儿童均报告其舒适度得到改善，并认为 MLD 有用。总之，MLD 被儿童接受度良好，但对 LE 肿胀的影响较差。然而，它通过移动淋巴液减少皮肤水肿。
