Department of Biosciences, Federal University of São Paulo, Campus Baixada Santista, Rua Silva Jardim, 136, Santos, SP, 11015-020, Brazil.
Department of Physiotherapy, Federal University of São Carlos (UFSCar), São Carlos, SP, Brazil.
Lasers Med Sci. 2020 Dec;35(9):1967-1974. doi: 10.1007/s10103-020-02989-1. Epub 2020 Mar 10.
To evaluate the effectiveness of an exercise program associated to photobiomodulation (PBM) on pain, postural changes, functionally, and muscular strength in women, one of the risk factors, with knee osteoarthritis (OA). A randomized controlled trial, with a blinded assessor and intention-to-treat analysis and placebo control. Sixty-two participants with knee OA (with confirmed radiological diagnosis) were evaluated for this study. However, 34 were considered eligible and were randomized into two groups: EPPG - exercise and PBM placebo group (n = 17) and EPAG - exercise and PBM active group (n = 16), but one participant was excluded of EPAG. The exercise program and PBM (808 nm, 100 mW/point, 4 J/point, 56 J total, 91 J/cm) were realized twice a week, during 8 weeks. West Ontario and the McMaster University Osteoarthritis Index (WOMAC) and Lequesne questionnaires, 1-repetition maximum test (1-RM) and posture evaluation software (SAPO) were used to analyze the effects of the therapies. In intragroup analysis, a significant improvement in pain WOMAC (p < 0.001), stiffness (p < 0.001), function (p < 0.001), Lequesne (p < 0.001), and 1-RM (all muscle groups) (p < 0.001) were observed. In this study, the exercise program improved pain, function, and muscle strength of all the participants. However, PBM, in the parameters used, did not optimize the effects of the exercise program in women with knee OA.
为了评估与光生物调节(PBM)相关的运动方案对患有膝骨关节炎(OA)这一风险因素的女性的疼痛、姿势变化、功能和肌肉力量的有效性,进行了一项随机对照试验,该试验具有盲法评估和意向治疗分析以及安慰剂对照。这项研究评估了 62 名患有膝骨关节炎的参与者。然而,有 34 名参与者被认为符合条件,并随机分为两组:EPPG - 运动和 PBM 安慰剂组(n = 17)和 EPAG - 运动和 PBM 活性组(n = 16),但 EPAG 组有一名参与者被排除在外。运动方案和 PBM(808nm,100mW/点,4J/点,56J 总剂量,91J/cm)每周进行两次,共进行 8 周。采用西部安大略省和麦克马斯特大学骨关节炎指数(WOMAC)和 Lequesne 问卷、1 次重复最大测试(1-RM)和姿势评估软件(SAPO)来分析治疗效果。在组内分析中,观察到疼痛 WOMAC(p<0.001)、僵硬(p<0.001)、功能(p<0.001)、Lequesne(p<0.001)和 1-RM(所有肌肉群)(p<0.001)均有显著改善。在这项研究中,运动方案改善了所有参与者的疼痛、功能和肌肉力量。然而,在使用的参数中,PBM 并没有优化患有膝骨关节炎的女性的运动方案的效果。