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Photobiomodulation therapy is not better than placebo in patients with chronic nonspecific low back pain: a randomised placebo-controlled trial.光生物调节疗法不比安慰剂在慢性非特异性下腰痛患者中更有效:一项随机安慰剂对照试验。
Pain. 2021 Jun 1;162(6):1612-1620. doi: 10.1097/j.pain.0000000000002189.
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Neglect of relevant treatment recommendations in the conduct and reporting of a laser therapy knee osteoarthritis trial: letter to the editor.激光疗法治疗膝骨关节炎试验的实施与报告中对相关治疗建议的忽视:致编辑的信
BMC Musculoskelet Disord. 2021 Jan 12;22(1):71. doi: 10.1186/s12891-020-03902-1.
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Association of photobiomodulation therapy (PBMT) and exercises programs in pain and functional capacity of patients with knee osteoarthritis (KOA): a systematic review of randomized trials.光生物调节疗法(PBMT)与运动计划对膝骨关节炎(KOA)患者疼痛和功能能力的影响:随机试验的系统评价
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Effects of different energy density low-level laser therapies for temporomandibular joint disorders patients: a systematic review and network meta-analysis of parallel randomized controlled trials.不同能量密度低水平激光疗法治疗颞下颌关节紊乱病患者的效果:平行随机对照试验的系统评价和网络荟萃分析。
Lasers Med Sci. 2021 Jul;36(5):1101-1108. doi: 10.1007/s10103-020-03197-7. Epub 2020 Nov 23.
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Photobiomodulation therapy does not decrease pain and disability in people with non-specific low back pain: a systematic review.光生物调节疗法不能减轻非特异性腰痛患者的疼痛和残疾:系统评价。
J Physiother. 2020 Jul;66(3):155-165. doi: 10.1016/j.jphys.2020.06.010. Epub 2020 Jul 14.
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Photobiomodulation Therapy is Able to Modulate PGE Levels in Patients With Chronic Non-Specific Low Back Pain: A Randomized Placebo-Controlled Trial.光生物调节疗法能够调节慢性非特异性下腰痛患者的前列腺素E水平:一项随机安慰剂对照试验。
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Exercise program combined with electrophysical modalities in subjects with knee osteoarthritis: a randomised, placebo-controlled clinical trial.运动方案联合电物理疗法治疗膝骨关节炎患者的随机、安慰剂对照临床试验。
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J Bone Joint Surg Am. 2020 May 20;102 Suppl 1(Suppl 1):3-9. doi: 10.2106/JBJS.20.00228.
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Level of pain, muscle strength and posture: effects of PBM on an exercise program in women with knee osteoarthritis - a randomized controlled trial.疼痛程度、肌肉力量和姿势:PBM 对膝骨关节炎女性运动计划的影响——一项随机对照试验。
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Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials.低水平激光疗法治疗膝骨关节炎疼痛和残疾的疗效:随机安慰剂对照试验的系统评价和荟萃分析。
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低强度激光和 LED(光生物调节疗法)治疗最常见的肌肉骨骼疾病的疼痛控制。

Low-intensity LASER and LED (photobiomodulation therapy) for pain control of the most common musculoskeletal conditions.

机构信息

Laboratory of Phototherapy and Innovative Technologies in Health (LaPIT), Postgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, Brazil.

Multi Radiance Medical, Solon, OH, USA.

出版信息

Eur J Phys Rehabil Med. 2022 Apr;58(2):282-289. doi: 10.23736/S1973-9087.21.07236-1. Epub 2021 Dec 16.

DOI:10.23736/S1973-9087.21.07236-1
PMID:34913330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9980499/
Abstract

Pain is the most common reason for physician consultations and the number one reason for missed work or school days is musculoskeletal pain. Pain management is utilized for easing the suffering and improving the Quality of Life of those living with chronic pain. Over the past several decades, physicians have become increasingly willing to prescribe opioids to manage pain. However, the opioid use can cause side effects as poor coordination, sedation, mood swings, depression, and anxiety combined with a dependence on the drugs. In the rehabilitation setting, patients benefit most when their health providers utilize a multimodal approach combining different types of therapies and when patients take on a significant role in optimal management of their own pain. The use of light as a therapeutic alternative form of medicine to manage pain and inflammation has been proposed to fill this void. Photobiomodulation therapy applied in the form of low-intensity Light Amplification by Stimulated Emission of Radiation (LASER) and light-emitting diode (LED) has been shown to reduce inflammation and swelling, promote healing, and reduce pain for an array of musculoskeletal conditions. There is evidence that photobiomodulation therapy reduces pain intensity in non-specific knee pain, osteoarthritis, pain post-total hip arthroplasty, fibromyalgia, temporomandibular diseases, neck pain, and low back pain. Therefore, the purpose of this paper was to present the up-to-dated evidence about the effects of low-intensity LASER and LED (photobiomodulation therapy) on pain control of the most common musculoskeletal conditions. We observed that the photobiomodulation therapy offers a non-invasive, safe, drug-free, and side-effect-free method for pain relief of both acute and chronic musculoskeletal conditions as well as fibromyalgia.

摘要

疼痛是医生就诊最常见的原因,而肌肉骨骼疼痛是导致缺勤或缺课的首要原因。疼痛管理用于减轻慢性疼痛患者的痛苦并提高其生活质量。在过去的几十年中,医生越来越愿意开阿片类药物来治疗疼痛。然而,阿片类药物的使用会导致副作用,如协调能力差、镇静、情绪波动、抑郁和焦虑,同时还会对药物产生依赖。在康复环境中,当医疗服务提供者采用结合不同类型治疗的多模式方法,并且患者在最佳管理自己的疼痛方面发挥重要作用时,患者会从中获益最大。已经提出将光作为一种替代药物治疗方法来管理疼痛和炎症,以填补这一空白。已经证明,应用于低强度光放大受激辐射(LASER)和发光二极管(LED)形式的光生物调节疗法可以减轻炎症和肿胀,促进愈合,并减轻多种肌肉骨骼疾病的疼痛。有证据表明,光生物调节疗法可以减轻非特异性膝关节疼痛、骨关节炎、全髋关节置换术后疼痛、纤维肌痛、颞下颌疾病、颈部疼痛和下腰痛的疼痛强度。因此,本文的目的是介绍低强度 LASER 和 LED(光生物调节疗法)对最常见肌肉骨骼疾病的疼痛控制效果的最新证据。我们观察到,光生物调节疗法为急性和慢性肌肉骨骼疾病以及纤维肌痛的疼痛缓解提供了一种非侵入性、安全、无药物和无副作用的方法。