伽玛刀立体定向放射外科在神经肿瘤学中的治疗作用
Therapeutic Role of Gamma Knife Stereotactic Radiosurgery in Neuro-Oncology.
作者信息
Desai Rupen, Rich Keith M
机构信息
Keith M. Rich, MD, MSMA member since 1986, is Professor of Neurosurgery, and Rupen Desai, MD, is Neurosurgery Resident PGY4, Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri.
出版信息
Mo Med. 2020 Jan-Feb;117(1):33-38.
The Gamma Knife Center of St. Louis has established itself as a key facility offering stereotactic radiosurgery (SRS) for a variety of neuro-oncologic disorders. Since the Gamma Knife unit was first brought to Washington University in 1997, we have treated 5,696 patients. In this review, we discuss the effective role of Gamma Knife SRS in the treatment strategies for patients with neuro-oncologic disorders including brain metastases, meningiomas, pituitary adenomas, and acoustic neuromas. While there is active ongoing research evaluating the most effective treatment for patients with these disorders, it is clear that best management practices may be tailored for individual patients utilizing SRS either alone or in conjunction alternative treatment strategies including open neurosurgical procedures, laser thermos-ablative surgery, and even new medical oncological treatment strategies.
圣路易斯伽马刀中心已成为一家关键机构，为各种神经肿瘤疾病提供立体定向放射外科治疗（SRS）。自1997年伽马刀设备首次引入华盛顿大学以来，我们已治疗了5696名患者。在本综述中，我们讨论了伽马刀SRS在神经肿瘤疾病患者治疗策略中的有效作用，这些疾病包括脑转移瘤、脑膜瘤、垂体腺瘤和听神经瘤。虽然目前正在积极开展研究，评估这些疾病患者的最有效治疗方法，但很明显，最佳管理方案可能是根据个体患者情况量身定制的，可单独使用SRS，也可结合其他替代治疗策略，包括开放性神经外科手术、激光热消融手术，甚至新的医学肿瘤治疗策略。
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