平均血小板体积、中性粒细胞与淋巴细胞比值及血小板与淋巴细胞比值作为复发性阿弗他口炎患者的炎症标志物
Mean Platelet Volume, Neutrophil-To-Lymphocyte Ratio, and Platelet-To-Lymphocyte Ratio as İnflammatory Markers in patients with Recurrent Aphthous Stomatitis.
作者信息
Karaer Isil Cakmak
机构信息
Department of Otolaryngology, Malatya Training and Research Hospital, Malatya, Turkey.
出版信息
Eurasian J Med. 2020 Feb;52(1):38-40. doi: 10.5152/eurasianjmed.2019.18486.
OBJECTIVE
The aim of this study is to examine the associations between white blood cell (WBC), hemoglobin (Hb), neutrophil, lymphocyte, platelet, mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels in patients with recurrent aphthous stomatitis (RAS).
MATERIALS AND METHODS
For this study, 137 patients with RAS and 137 healthy controls were recruited. The study participants had no systemic diseases except RAS. Serum WBC, Hb, neutrophil, lymphocyte, platelet, MPV, PLR, NLR, ESR, and CRP levels were recorded in the active period for all patients with RAS and controls.
RESULTS
There was no statistically significant difference in the WBC, Hb, neutrophil, lymphocyte, platelet, MPV, NLR PLR, ESR, and CRP levels between patients with RAS and controls.
CONCLUSION
No differences were observed for WBC, Hb, neutrophil, lymphocyte, platelet, MPV, NLR, PLR, ESR, and CRP levels between patients with RAS and controls. These parameters therefore cannot be used as markers for inflammation or inflammation severity in patients with RAS.
目的
本研究旨在探讨复发性阿弗他口炎（RAS）患者的白细胞（WBC）、血红蛋白（Hb）、中性粒细胞、淋巴细胞、血小板、平均血小板体积（MPV）、中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）、红细胞沉降率（ESR）和C反应蛋白（CRP）水平之间的关联。
材料与方法
本研究招募了137例RAS患者和137名健康对照者。研究参与者除RAS外无其他全身性疾病。记录所有RAS患者和对照者在急性期的血清WBC、Hb、中性粒细胞、淋巴细胞、血小板、MPV、PLR、NLR、ESR和CRP水平。
结果
RAS患者与对照者之间的WBC、Hb、中性粒细胞、淋巴细胞、血小板、MPV、NLR、PLR、ESR和CRP水平无统计学显著差异。
结论
RAS患者与对照者之间在WBC、Hb、中性粒细胞、淋巴细胞、血小板、MPV、NLR、PLR、ESR和CRP水平上未观察到差异。因此，这些参数不能用作RAS患者炎症或炎症严重程度的标志物。
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