Demir Emine, Celiker Metin, Aydogan Elif, Balaban Gokce Aydin, Dursun Engin
Department of Otorhinolaryngology, Faculty of Medicine, Recep Tayyip Erdogan University, Sehitler Street, No:74, Rize, Turkey.
Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):8-13. doi: 10.1007/s12070-019-01709-8. Epub 2019 Jul 25.
The aim of our study was to obtain wideband tympanometry (WBT) findings in Meniere's disease (MD). It also aimed to evaluate whether the data obtained have diagnostic significance. 21 patients who were followed-up for unilateral Meniere's Disease were evaluated. The ears with Meniere disease were grouped as the MD group and the opposite ears were grouped as the control group. WBT results were recorded as resonance frequency (RF) and frequency-specific absorbance values at 10 different frequencies in the 0.25-8.0 kHz range. Statistical analysis was performed with test and receiver-operating characteristic analysis. Considering the WBT results, RF was significantly lower in the MD group compared to the control group ( < 0.001). Frequency-specific absorbance values at 0.25, 0.5, 0.75 and 1 kHz were significantly lower in the MD group compared to the control group ( < 0.05). No significant difference was found at 1.5 kHz and above ( > 0.05). For the MD, the RF below 598 Hz was 85.7% sensitive and 76.2% specific, the absorbance at 0.25 kHz below 8% was 66.7% sensitive and 61.9% specific, the absorbance below 17% at 0.5 kHz was 71.4% sensitive and 62.1% specific, the absorbance below 36% at 0.75 kHz was 81% sensitive and 57.8% specific, and the absorbance below 46% at 1 kHz was 71.5% sensitive and 66.7% specific. When MD was compared with intact ears, it was observed that RF was lower, and absorbance decreased in low frequencies. These data is statistically significant, but the sensitivity level is not enough for diagnostic use. Therefore, it is considered as an complementary test for the diagnosis.
我们研究的目的是获取梅尼埃病（MD）的宽带鼓室图（WBT）结果。其还旨在评估所获得的数据是否具有诊断意义。对21例接受单侧梅尼埃病随访的患者进行了评估。将患梅尼埃病的耳分为MD组，对侧耳分为对照组。WBT结果记录为共振频率（RF）以及在0.25 - 8.0kHz范围内10个不同频率处的频率特异性吸光度值。采用检验和受试者操作特征分析进行统计分析。考虑WBT结果，MD组的RF显著低于对照组（<0.001）。MD组在0.25、0.5、0.75和1kHz处的频率特异性吸光度值显著低于对照组（<0.05）。在1.5kHz及以上未发现显著差异（>0.05）。对于MD，低于598Hz的RF敏感性为85.7%，特异性为76.2%，0.25kHz处低于8%的吸光度敏感性为66.7%，特异性为61.9%，0.5kHz处低于17%的吸光度敏感性为71.4%，特异性为62.1%，0.75kHz处低于36%的吸光度敏感性为81%，特异性为57.8%，1kHz处低于46%的吸光度敏感性为71.5%，特异性为66.7%。当将MD与正常耳进行比较时，观察到RF较低，且低频吸光度降低。这些数据具有统计学意义，但敏感性水平不足以用于诊断。因此，它被视为诊断的一项补充检查。
