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通过连续心脏磁共振成像和正电子发射断层扫描辅助的老年心脏淋巴瘤治疗决策

Treatment Decisions in Geriatric Cardiac Lymphoma Facilitated by Serial Cardiac Magnetic Resonance Imaging and Positron Emission Tomography.

作者信息

Pollak P Timothy, Brar Gurbir, Poinen Krishna, Lydell Carmen P

机构信息

Departments of Medicine, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Cardiac Sciences, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada.

出版信息

CJC Open. 2019 Apr 13;1(3):153-157. doi: 10.1016/j.cjco.2019.03.001. eCollection 2019 May.

DOI:10.1016/j.cjco.2019.03.001
PMID:32159100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7063661/
Abstract

A tumour encasing the right coronary was identified on computed tomography pulmonary embolism protocol in an 81-year-old man. Concerns regarding tolerability of chemotherapy in an octogenarian were addressed using cardiac magnetic resonance imaging to monitor a trial of modified-chemotherapy for his primary cardiac B-cell lymphoma. Residual activity on positron emission tomography computed tomography mandated consolidation with radiotherapy to achieve a tumor-free return to health. Despite advanced age, successful therapy in this, the oldest case of primary cardiac lymphoma reported, was facilitated by monitoring treatment effectiveness with advanced cardiac imaging and the use of standardized frailty scores in communicating his appropriate level of robustness for tolerating chemotherapy.

摘要

在一名81岁男性的计算机断层扫描肺栓塞检查方案中发现了一个包裹右冠状动脉的肿瘤。通过心脏磁共振成像来监测针对其原发性心脏B细胞淋巴瘤的改良化疗试验,解决了对一名八旬老人化疗耐受性的担忧。正电子发射断层扫描计算机断层扫描上的残留活性要求进行放疗巩固治疗,以实现无肿瘤的康复。尽管患者年事已高,但在这个已报道的最年长的原发性心脏淋巴瘤病例中,通过先进的心脏成像监测治疗效果以及使用标准化衰弱评分来传达其耐受化疗的适当强健程度,使得成功治疗成为可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81de/7063661/940c29660245/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81de/7063661/aefd64008775/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81de/7063661/940c29660245/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81de/7063661/aefd64008775/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81de/7063661/940c29660245/gr2.jpg

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本文引用的文献

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Diffuse large B-cell lymphoma (DLBCL): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.弥漫性大B细胞淋巴瘤(DLBCL):ESMO诊断、治疗及随访临床实践指南
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