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血管性痴呆临床诊断的准确性:一项前瞻性临床与尸检神经病理学研究。

Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study.

作者信息

Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A

机构信息

Department of Neurology, University of Helsinki, Finland.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Aug;51(8):1037-44. doi: 10.1136/jnnp.51.8.1037.

Abstract

Brains from a prospective study of demented patients were investigated post mortem. Of the 27 patients with clinical diagnosis of vascular dementia, 23 showed multiple cerebral infarcts but senile plaques and neurofibrillary tangles were absent or in insignificant numbers. This gives an accuracy of 85%, a figure higher than previously documented.

摘要

对一组患有痴呆症的患者进行前瞻性研究,其大脑在死后进行了调查。在临床诊断为血管性痴呆的27名患者中,23名显示有多处脑梗死,但没有或仅有少量老年斑和神经原纤维缠结。这给出了85%的准确率,该数字高于先前记录的数字。

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