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18 岁以下日本患者葡萄膜炎的临床特征和视力预后。

Clinical Features and Visual Outcome of Uveitis in Japanese Patients Younger than 18 Years.

机构信息

Department of Ophthalmology, Tokyo Metropolitan Geriatric Medical Center, Itabashi-Ku, Tokyo, Japan.

Department of Ophthalmology, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.

出版信息

Ocul Immunol Inflamm. 2021 Nov 17;29(7-8):1280-1286. doi: 10.1080/09273948.2020.1726972. Epub 2020 Mar 12.

Abstract

: To investigate the clinical features and visual outcome of young Japanese patients with uveitis.: Patients younger than 18 years who presented with uveitis at the University of Tokyo Hospital between 2000 and 2018 were retrospectively reviewed.: The study comprised 98 patients whose mean age was 12.3 ± 3.8 years. Anterior uveitis was present in 52.0%, panuveitis in 37.8%, and posterior uveitis in 10.2%. The most common diagnosis was juvenile chronic iridocyclitis (JCI) (29.6%) followed by tubulointerstitial nephritis and uveitis syndrome (4.1%) and neuroretinitis (4.1%). Thirty-nine patients received systemic anti-inflammatory treatment. Among all subjects, 56% presented with ocular complications and 20% underwent ocular surgery. Visual acuity of 20/200 or less was observed in 6.2%. The common causes of decreased vision were hypotony, serous retinal detachment, and pupil disorder.: JCI was the most common diagnosis. Hypotony, serous retinal detachment, and pupil disorder can lead to visual loss.

摘要

: 目的:探讨日本年轻葡萄膜炎患者的临床特征和视力预后。: 本研究回顾性分析了 2000 年至 2018 年期间在东京大学医院就诊的年龄小于 18 岁的葡萄膜炎患者。: 共纳入 98 例患者,平均年龄为 12.3 ± 3.8 岁。前葡萄膜炎占 52.0%,全葡萄膜炎占 37.8%,后葡萄膜炎占 10.2%。最常见的诊断是幼年特发性关节炎(JIA)相关的慢性前葡萄膜炎(29.6%),其次是 tubulointerstitial nephritis and uveitis syndrome(4.1%)和神经视网膜炎(4.1%)。39 例患者接受了全身抗炎治疗。所有患者中,56%出现眼部并发症,20%接受了眼部手术。视力低于 20/200 的占 6.2%。视力下降的常见原因包括低眼压、浆液性视网膜脱离和瞳孔障碍。: JIA 是最常见的诊断。低眼压、浆液性视网膜脱离和瞳孔障碍可导致视力丧失。

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