肌肉减少症对一组黎巴嫩绝经后妇女的髋关节结构分析变量有负面影响。

Sarcopenia negatively affects hip structure analysis variables in a group of Lebanese postmenopausal women.

机构信息

Department of Physical Education, University of Balamand, Kelhat, El-Koura, Lebanon.

I3MTO, EA4708, Université d'Orléans, Orléans, France.

出版信息

BMC Bioinformatics. 2020 Mar 11;21(Suppl 2):86. doi: 10.1186/s12859-020-3353-9.

DOI:10.1186/s12859-020-3353-9

PMID:32164524

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7068911/

Abstract

BACKGROUND

The current study's purpose is to compare hip structural analysis variables in a group of postmenopausal women with sarcopenia and another group of postmenopausal women with normal skeletal muscle mass index. To do so, the current study included 8 postmenopausal women (whose ages ranged between 65 and 84 years) with sarcopenia and 60 age-matched controls (with normal skeletal muscle mass index (SMI)). Body composition and bone parameters were evaluated by dual-energy X-ray absorptiometry (DXA).

RESULTS

Weight, lean mass, body mass index, femoral neck cross-sectional area (FN CSA), FN section modulus (Z), FN cross sectional moment of inertia (CSMI), intertrochanteric (IT) CSA, IT Z, IT CSMI, IT cortical thickness (CT), femoral shaft (FS) CSA, FS Z and FS CSMI were significantly greater (p < 0.05) in women with normal SMI compared to women with sarcopenia. In the whole population, SMI was positively associated with IT CSA, IT Z, IT CSMI, IT CT, FS CSA, FS Z, FS CSMI, FS CT but negatively correlated to IT buckling ratio (BR) and FS BR.

CONCLUSION

The current study suggests that sarcopenia has a negative effect on hip bone strength indices in postmenopausal women.

摘要

背景

本研究旨在比较患有肌少症的绝经后女性和具有正常骨骼肌质量指数的绝经后女性的髋部结构分析变量。为此，本研究纳入了 8 名患有肌少症的绝经后女性（年龄在 65 至 84 岁之间）和 60 名年龄匹配的对照组（具有正常骨骼肌质量指数（SMI））。通过双能 X 线吸收法（DXA）评估身体成分和骨参数。

结果

体重、瘦体重、体重指数、股骨颈横截面积（FN CSA）、FN 截面模数（Z）、FN 截面惯性矩（CSMI）、转子间区 CSA、转子间区 Z、转子间区 CSMI、转子间区皮质厚度（CT）、股骨干 CSA、股骨干 Z 和股骨干 CSMI 在具有正常 SMI 的女性中显著大于（p < 0.05）患有肌少症的女性。在整个人群中，SMI 与 IT CSA、IT Z、IT CSMI、IT CT、FS CSA、FS Z 和 FS CSMI 呈正相关，与 IT 屈曲比（BR）和 FS BR 呈负相关。