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中国一家三级儿科医院呼吸科门诊就诊和诊断的年龄和性别趋势:一项 10 年回顾性研究。

Age- and gender-specific trends in respiratory outpatient visits and diagnoses at a tertiary pediatric hospital in China: a 10-year retrospective study.

机构信息

Department of Data Management and Statistics, Children's Hospital of Fudan University, Shanghai, China.

Department of Respiratory Disease, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.

出版信息

BMC Pediatr. 2020 Mar 12;20(1):115. doi: 10.1186/s12887-020-2001-x.

Abstract

BACKGROUND

Respiratory infections are one of three leading causes of childhood mortality, and worldwide increase and recent plateau in childhood asthma has been reported. However, data on trends of respiratory diseases over long period of time is limited. This study aimed to determine the trends of respiratory disease outpatient visits (ROVs) and diagnoses (RODs) in one of the largest children's teaching hospitals in China between 2009 and 2018.

METHODS

A retrospective study based on routine administrative data was designed and implemented according to the RECORD statement. Demographic details and diagnoses of the outpatients < 18 years visiting the respiratory department of the hospital were extracted from the Hospital Information System. Age- and gender-specific trends were illustrated by calculating average annual growth rate (AAGR) for ROVs and comparing change of proportion for different RODs over time.

RESULTS

There were 698,054 ROVs from 285,574 children (40.4% female). AAGR of ROVs was 15.2%. Children aged 4 to < 7 years had a faster increase than other age groups. Bronchitis (27.6%), pneumonia (18.5%), pneumonia affecting other systems (18.4%), asthma and status asthmaticus (10.7%), and vasomotor and allergic rhinitis (9.2%) accounted for 84.4% of all RODs. The proportion of bronchitis decreased across years, with the concomitant increasing trend in the proportion of pneumonia. Age-specific trend in diagnoses showed greater proportion of asthma in all visits for the children aged 7 to < 18 years than younger children. Gender-specific trend in diagnoses showed the proportion of asthma was greater for males but the AAGR was greater for females.

CONCLUSION

The persistent upward trend in ROVs was observed among children at different ages and a gender difference was also seen. In contrast to what has been reported, burden of asthma and allergies diseases continues to increase locally.

摘要

背景

呼吸道感染是导致儿童死亡的三大原因之一,全球范围内儿童哮喘的发病率呈上升趋势且近年来趋于平稳。然而,长期以来关于呼吸道疾病趋势的数据有限。本研究旨在确定中国最大的儿童教学医院之一的呼吸科门诊量(ROV)和诊断(ROD)在 2009 年至 2018 年间的趋势。

方法

根据 RECORD 声明,我们设计并实施了一项基于常规行政数据的回顾性研究。从医院信息系统中提取了在医院呼吸科就诊的<18 岁门诊患者的人口统计学细节和诊断信息。通过计算 ROV 的年均增长率(AAGR)并比较不同 ROD 随时间的比例变化,展示了按年龄和性别划分的趋势。

结果

共有 285574 名儿童的 698054 次 ROV(40.4%为女性)。ROV 的 AAGR 为 15.2%。4 至<7 岁的儿童增长速度快于其他年龄组。支气管炎(27.6%)、肺炎(18.5%)、肺炎累及其他系统(18.4%)、哮喘和哮喘持续状态(10.7%)和血管舒缩性和过敏性鼻炎(9.2%)占所有 ROD 的 84.4%。各年度支气管炎的比例呈下降趋势,肺炎的比例呈上升趋势。按年龄划分的诊断趋势显示,7 至<18 岁儿童的所有就诊中哮喘的比例较高,而较年轻的儿童则较低。按性别划分的诊断趋势显示,哮喘的比例男性较高,但增长率女性较高。

结论

不同年龄段的儿童的 ROV 持续呈上升趋势,且存在性别差异。与已报道的情况相反,局部地区哮喘和过敏疾病的负担持续增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94ce/7068978/60f3d8eff212/12887_2020_2001_Fig1_HTML.jpg

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