特发性颅内高压患者中央角膜厚度与视乳头水肿之间的关系缺乏相关性。
Lack of Relationship between Central Corneal Thickness and Papilloedema in Idiopathic Intracranial Hypertension.
作者信息
Peragallo Jason H, Vasseneix Caroline, Dattilo Michael, Newman Nancy J, Biousse Valérie, Bruce Beau B
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA.
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
Neuroophthalmology. 2019 Mar 14;43(6):371-374. doi: 10.1080/01658107.2019.1588337. eCollection 2019 Dec.
Translaminar pressure gradient abnormalities have been implicated in the pathogenesis and progression of glaucoma. A "reversed" translaminar pressure gradient may be related to papilloedema severity in idiopathic intracranial hypertension. Central corneal thickness is related to intraocular pressure measurements and, by extension, to translaminar pressure gradients. We evaluated if central corneal thickness could be a marker of worse papilloedema due to altered translaminar pressure gradients in patients with idiopathic intracranial hypertension. We found that central corneal thickness was not related to the severity of papilloedema in idiopathic intracranial hypertension.
跨筛板压力梯度异常与青光眼的发病机制和进展有关。“反向”跨筛板压力梯度可能与特发性颅内高压患者的视乳头水肿严重程度有关。中央角膜厚度与眼压测量有关，进而与跨筛板压力梯度有关。我们评估了在特发性颅内高压患者中，中央角膜厚度是否可能因跨筛板压力梯度改变而成为视乳头水肿加重的一个指标。我们发现，中央角膜厚度与特发性颅内高压患者视乳头水肿的严重程度无关。
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