Holtfreter Birte, Samietz Stefanie, Hertrampf Katrin, Aarabi Ghazal, Hagenfeld Daniel, Kim Ti-Sun, Kocher Thomas, Koos Bernd, Schmitter Marc, Ahrens Wolfgang, Alwers Elizabeth, Becher Heiko, Berger Klaus, Brenner Hermann, Damms-Machado Antje, Ebert Nina, Fischer Beate, Franzke Claus-Werner, Frölich Stefanie, Greiser Halina, Gies Anton, Günther Kathrin, Hassan Lamiaa, Hoffmann W, Jaeschke Lina, Keil Thomas, Kemmling Yvonne, Krause Gérard, Krist Lilian, Legath Nicole, Lieb Wolfgang, Leitzmann Michael, Linseisen Jakob, Loeffler Markus, Meinke-Franze Claudia, Michels Karin B, Mikolajczyk Rafael, Obi Nadia, Peters Annette, Pischon Tobias, Schipf Sabine, Schmidt Börge, Völzke Henry, Waniek Sabina, Wigmann Claudia, Wirkner Kerstin, Schmidt Carsten Oliver, Kühnisch Jan, Rupf Stefan
Poliklinik für Zahnerhaltung, Parodontologie, Endodontologie, Präventive Zahnmedizin und Kinderzahnheilkunde, Universitätsmedizin Greifswald, Greifswald, Deutschland.
Poliklinik für Zahnärztliche Prothetik, Alterszahnheilkunde und Medizinische Werkstoffkunde, Universitätsmedizin Greifswald, Greifswald, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Apr;63(4):426-438. doi: 10.1007/s00103-020-03107-w.
Caries and periodontitis are highly prevalent worldwide. Because detailed data on these oral diseases were collected within the framework of the German National Cohort (GNC), associations between oral and systemic diseases and conditions can be investigated.
The study protocol for the oral examination was designed to ensure a comprehensive collection of dental findings by trained non-dental staff within a limited examination time. At the mid-term of the GNC baseline examination, a first quality evaluation was performed to check the plausibility of results and to propose measures to improve the data quality.
A dental interview, saliva sampling and oral diagnostics were conducted. As part of the level‑1 examination, the number of teeth and prostheses were recorded. As part of the level‑2 examination, detailed periodontal, cariological and functional aspects were examined. All examinations were conducted by trained non-dental personnel. Parameters were checked for plausibility and variable distributions were descriptively analysed.
Analyses included data of 57,967 interview participants, 56,913 level‑1 participants and 6295 level‑2 participants. Percentages of missing values for individual clinical parameters assessed in level 1 and level 2 ranged between 0.02 and 3.9%. Results showed a plausible distribution of the data; rarely, implausible values were observed, e.g. for measurements of horizontal and vertical overbite (overjet and overbite). Intra-class correlation coefficients indicated differences in individual parameters between regional clusters, study centres and across different examiners.
The results confirm the feasibility of the study protocol by non-dental personnel and its successful integration into the GNC's overall assessment program. However, rigorous dental support of the study centres is required for quality management.
龋齿和牙周炎在全球范围内高度流行。由于这些口腔疾病的详细数据是在德国国民队列（GNC）框架内收集的，因此可以研究口腔疾病与全身疾病及状况之间的关联。
口腔检查的研究方案旨在确保经过培训的非牙科工作人员在有限的检查时间内全面收集牙科检查结果。在GNC基线检查的中期，进行了首次质量评估，以检查结果的合理性并提出提高数据质量的措施。
进行了牙科访谈、唾液采样和口腔诊断。作为一级检查的一部分，记录了牙齿和假牙的数量。作为二级检查的一部分，对牙周、龋病和功能方面进行了详细检查。所有检查均由经过培训的非牙科人员进行。检查参数的合理性，并对变量分布进行描述性分析。
分析包括57967名访谈参与者、56913名一级参与者和6295名二级参与者的数据。在一级和二级评估中评估的各个临床参数的缺失值百分比在0.02%至3.9%之间。结果显示数据分布合理；很少观察到不合理的值，例如水平和垂直覆盖（覆盖和覆合）的测量值。组内相关系数表明区域集群、研究中心和不同检查人员之间各个参数存在差异。
结果证实了非牙科人员执行研究方案的可行性及其成功纳入GNC的整体评估计划。然而，质量管理需要研究中心提供严格的牙科支持。
