Hassenstein Max J, Aarabi Ghazal, Ahnert Peter, Becher Heiko, Franzke Claus-Werner, Fricke Julia, Krause Gérard, Glöckner Stephan, Gottschick Cornelia, Karch André, Kemmling Yvonne, Kerrinnes Tobias, Lange Berit, Mikolajczyk Rafael, Nieters Alexandra, Ott Jördis J, Ahrens Wolfgang, Berger Klaus, Meinke-Franze Claudia, Gastell Sylvia, Günther Kathrin, Greiser Karin Halina, Holleczek Bernd, Horn Johannes, Jaeschke Lina, Jagodzinski Annika, Jansen Lina, Jochem Carmen, Jöckel Karl-Heinz, Kaaks Rudolf, Krist Lilian, Kuß Oliver, Langer Susan, Legath Nicole, Leitzmann Michael, Lieb Wolfgang, Loeffler Markus, Mangold Nina, Michels Karin B, Meisinger Christa, Obi Nadia, Pischon Tobias, Schikowski Tamara, Schipf Sabine, Schulze Matthias B, Stang Andreas, Waniek Sabina, Wirkner Kerstin, Willich Stefan N, Castell Stefanie
Abteilung für Epidemiologie, Helmholtz-Zentrum für Infektionsforschung GmbH (HZI), Inhoffenstraße 7, 38124, Braunschweig, Deutschland.
PhD Programme "Epidemiology" Braunschweig-Hannover, Braunschweig, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Apr;63(4):404-414. doi: 10.1007/s00103-020-03114-x.
Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the development of non-communicable diseases. Analyses of the German National Cohort (GNC) may provide deeper insights into this issue and pave the way for new targeted approaches in disease prevention.
The aim was to describe the tools used to assess infectious diseases and to present initial data on infectious disease frequencies, as well as to relate the GNC assessment tools to data collection methods in other studies in Germany.
As part of the baseline examination, questions regarding infectious diseases were administered using both an interview and a self-administered touchscreen questionnaire. Data from the initial 101,787 GNC participants were analysed.
In the interview, 0.2% (HIV/AIDS) to 8.6% (shingles) of respondents reported ever having a medical diagnosis of shingles, postherpetic neuralgia (in cases where shingles was reported), hepatitis B/C, HIV/AIDS, tuberculosis or sepsis if treated in hospital. In the questionnaire, 12% (cystitis) to 81% (upper respiratory tract infections) of respondents reported having experienced at least one occurrence of upper or lower respiratory tract infections, gastrointestinal infections, cystitis or fever within the past 12 months.
The cross-sectional analyses of data and tools presented here - for example on determinants of susceptibility to self-reported infections - can be anticipated from the year 2021 onward. Beyond that, more extensive research into infectious disease epidemiology will follow, particularly once analyses of GNC biological materials have been performed.
在德国，传染病在疾病认知、卫生经济考量及公共卫生方面持续发挥着重要作用。近年来，传染病与非传染性疾病的发展存在关联。对德国国民队列（GNC）的分析可能会为这一问题提供更深入的见解，并为疾病预防的新靶向方法铺平道路。
旨在描述用于评估传染病的工具，呈现传染病频率的初始数据，并将GNC评估工具与德国其他研究中的数据收集方法相关联。
作为基线检查的一部分，通过访谈和自填式触摸屏问卷来询问有关传染病的问题。对GNC最初的101,787名参与者的数据进行了分析。
在访谈中，0.2%（艾滋病毒/艾滋病）至8.6%（带状疱疹）的受访者报告曾被医学诊断患有带状疱疹、带状疱疹后神经痛（在报告患有带状疱疹的情况下）、乙型/丙型肝炎、艾滋病毒/艾滋病、结核病或败血症（若在医院接受治疗）。在问卷中，12%（膀胱炎）至81%（上呼吸道感染）的受访者报告在过去12个月内至少发生过一次上呼吸道或下呼吸道感染、胃肠道感染、膀胱炎或发烧。
此处呈现的数据和工具的横断面分析——例如关于自我报告感染易感性的决定因素——预计从2021年起可得。除此之外，将开展更广泛的传染病流行病学研究，尤其是一旦对GNC生物材料进行了分析之后。
