Department of Psychiatry, University of Campania "Luigi Vanvitelli,"Naples, Italy.
Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Eur Psychiatry. 2020 Mar 13;63(1):e26. doi: 10.1192/j.eurpsy.2019.8.
Schizophrenia is a leading cause of disability. People living with schizophrenia (PLWS) present unemployment, social isolation, excess mortality and morbidity, and poor quality of life. Early recognition and appropriate treatment reduce the risk of chronicity and comorbidity. Personalization and integration of pharmacological and psychosocial interventions, as well as accurate identification and management of psychiatric and somatic comorbidities, can significantly improve mental and physical health of PLWS, promoting recovery.
A three-step Delphi approach was used to explore consensus on the essential components of early recognition and intervention, personalization, and integration of care to improve schizophrenia outcome, and on barriers and challenges to close treatment gaps. The consensus involved 8 Italian experts of schizophrenia, 100 psychiatrists from academic and nonacademic settings, including representatives of Italian Society of Psychiatry, and 65 trainees in psychiatry.
A strong consensus (from mostly agree to totally agree) emerged on the importance of early diagnosis (97%), standardized assessments (91%), correct management of somatic and psychiatric comorbidities (99%), and personalization and integration of care (94%). Lack of time, human resources, and training were identified as the main barriers and challenges to the translation of knowledge into clinical practice.
The results of this Delphi study demonstrated a strong consensus on main components of schizophrenia care, as well as on unmet needs to promote best practice and gaps between knowledge and clinical practice. The involvement of a large group of professionals and trainees in this in-depth consensus process might contribute to raise awareness and stimulate innovative strategies to improve the outcome of PLWS.
精神分裂症是导致残疾的主要原因。精神分裂症患者(PLWS)存在失业、社会孤立、过高的死亡率和发病率以及较差的生活质量。早期识别和适当治疗可降低慢性和合并症的风险。个性化和整合药物治疗和心理社会干预,以及准确识别和管理精神和躯体共病,可以显著改善 PLWS 的身心健康,促进康复。
采用三步德尔菲法探讨早期识别和干预、个性化和整合护理的基本要素,以改善精神分裂症的结果,以及解决缩小治疗差距的障碍和挑战。共识涉及 8 名意大利精神分裂症专家、100 名来自学术和非学术环境的精神科医生,包括意大利精神病学学会的代表,以及 65 名精神病学实习生。
早期诊断(97%)、标准化评估(91%)、正确管理躯体和精神共病(99%)以及个性化和整合护理(94%)的重要性得到了强烈共识(从大多数同意到完全同意)。缺乏时间、人力资源和培训被确定为将知识转化为临床实践的主要障碍和挑战。
这项德尔菲研究的结果表明,在精神分裂症护理的主要内容以及促进最佳实践和知识与临床实践之间差距方面存在强烈共识。大量专业人员和实习生参与这一深入的共识过程可能有助于提高认识并激发创新策略,以改善 PLWS 的预后。