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营养在哮喘预防和治疗中的作用。

The role of nutrition in asthma prevention and treatment.

机构信息

Physicians Committee for Responsible Medicine, Washington, DC, USA.

George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

出版信息

Nutr Rev. 2020 Nov 1;78(11):928-938. doi: 10.1093/nutrit/nuaa005.

Abstract

Asthma is a chronic respiratory condition characterized by airway inflammation and hyperreactivity. Prevalence has continued to rise in recent decades as Western dietary patterns have become more pervasive. Evidence suggests that diets emphasizing the consumption of plant-based foods might protect against asthma development and improve asthma symptoms through their effects on systemic inflammation, oxidation, and microbial composition. Additionally, increased fruit and vegetable intake, reduced animal product consumption, and weight management might mediate cytokine release, free radical damage, and immune responses involved in the development and course of asthma. The specific aim of this review paper is to examine the current literature on the associations between dietary factors and asthma risk and control in children and adults. Clinical trials examining the mechanism(s) by which dietary factors influence asthma outcomes are necessary to identify the potential use of nutritional therapy in the prevention and management of asthma.

摘要

哮喘是一种慢性呼吸系统疾病,其特征是气道炎症和高反应性。随着西方饮食模式的普及,近几十年来哮喘的发病率持续上升。有证据表明,强调食用植物性食物的饮食可能通过对全身炎症、氧化和微生物组成的影响来预防哮喘的发生并改善哮喘症状。此外,增加水果和蔬菜的摄入量、减少动物产品的摄入以及体重管理可能会调节细胞因子释放、自由基损伤以及与哮喘发展和病程相关的免疫反应。本综述论文的具体目的是检查目前关于饮食因素与儿童和成人哮喘风险和控制之间关系的文献。有必要进行临床试验来研究饮食因素影响哮喘结果的机制,以确定营养疗法在预防和管理哮喘中的潜在用途。

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