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韩国成年人的上睑下垂:与年龄相关的患病率和评估的临界年龄。

Blepharoptosis among Korean adults: age-related prevalence and threshold age for evaluation.

机构信息

Department of Ophthalmology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Department of Biostatistics, The Catholic University of Korea, 222 Banpo-daero, Seocho-Gu, Seoul, 137-701, South Korea.

出版信息

BMC Ophthalmol. 2020 Mar 13;20(1):99. doi: 10.1186/s12886-020-01350-y.

Abstract

BACKGROUND

To evaluate the prevalence of blepharoptosis among Korean adults and the characteristics of blepharoptosis patients, and to determine an appropriate age threshold for recommending blepharoptosis evaluation.

METHODS

The Korean National Health and Nutrition Examination Survey (KNHANES-V) was conducted in 2010-2012. We extracted data on 17,878 Korean adults aged more than and equal to 19 years included in KNHANES-V, and determined blepharoptosis prevalence according to age, to determine the cutoff age for recommending blepharoptosis evaluation. We also determined the possible association between blepharoptosis and obesity parameters, such as body mass index (BMI) and waist circumference (WC).

RESULTS

There was astrong association between older age and the prevalence of blepharoptosis. The cutoff age for recommending blepharoptosis evaluation was 63 years for males, 70 years for females, and 66 years for all patients. Patients with a high BMI and large WC had a higher prevalence of blepharoptosis in all age groups except for those aged over 80 years. The association of blepharoptosis with BMI according to age group showed that in the 50-59 and 60-69 years age groups, blepharoptosis prevalence and BMI were higher. However, in the 70-79 and 80-89 years age groups, extremely obese patients (BMI > 30) showed a decreased blepharoptosis prevalence.

CONCLUSIONS

Moderate to severe blepharoptosis can result in poor visual function and exacerbate headaches and depression, leading to decreased quality of life. This study proposed an appropriate age threshold for recommending evaluation of patients with blepharoptosis among the general population of Korea.

摘要

背景

评估韩国成年人中眼睑下垂的患病率以及眼睑下垂患者的特征,并确定推荐眼睑下垂评估的适当年龄阈值。

方法

我们对 2010-2012 年进行的韩国国家健康和营养检查调查(KNHANES-V)的数据进行了提取,共纳入了 17878 名年龄大于等于 19 岁的韩国成年人。根据年龄确定了眼睑下垂的患病率,以确定推荐眼睑下垂评估的截止年龄。我们还确定了眼睑下垂与肥胖参数(如体重指数[BMI]和腰围[WC])之间可能存在的关联。

结果

年龄与眼睑下垂的患病率之间存在很强的关联。推荐眼睑下垂评估的截止年龄为男性 63 岁,女性 70 岁,所有患者为 66 岁。在所有年龄组中,除了 80 岁以上的患者外,BMI 和 WC 较高的患者眼睑下垂的患病率更高。根据年龄组的眼睑下垂与 BMI 的关联显示,在 50-59 岁和 60-69 岁年龄组中,眼睑下垂的患病率和 BMI 更高。然而,在 70-79 岁和 80-89 岁年龄组中,BMI 较高的极度肥胖患者(BMI>30)眼睑下垂的患病率降低。

结论

中度至重度眼睑下垂会导致视力不佳,并加重头痛和抑郁,从而降低生活质量。本研究提出了韩国普通人群中推荐眼睑下垂评估的适当年龄阈值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a06/7071706/2cdd45a93c19/12886_2020_1350_Fig1_HTML.jpg

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