Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02215, USA.
Department of Imaging, Harvard Medical School, Dana Farber Cancer Institute, Boston, MA, USA.
Abdom Radiol (NY). 2020 Dec;45(12):3982-3989. doi: 10.1007/s00261-020-02474-x.
Currently there is a lot of interest in the use of a "biparametric" or "abbreviated" prostate MR protocol, which usually refers to removal of the dynamic contrast-enhanced (DCE) MRI, in the detection of clinically significant prostate cancer. In this article we describe the benefits of DCE as part of the PI-RADS lexicon, with particular reference to its role in PI-RADS V2 category 3 peripheral zone lesions. We also discuss the benefits of triplanar T2-weighted images, and finally discuss how a mpMRI protocol is of benefit in prostate cancer staging, in evaluating for local disease recurrence, and as a biomarker for neoadjuvant therapy response.
目前，人们对使用“双参数”或“简化”前列腺磁共振（MR）方案检测临床显著前列腺癌很感兴趣，这种方案通常是指去除动态对比增强（DCE）MRI。本文描述了 DCE 作为 PI-RADS 词汇的一部分的优势，特别提到了其在 PI-RADS V2 第 3 类外周带病变中的作用。还讨论了三平面 T2 加权成像的优势，最后讨论了 mpMRI 方案如何有益于前列腺癌分期、评估局部疾病复发以及作为新辅助治疗反应的生物标志物。
