用于猪流感的病原体分型和疫苗效力的体内模型。
In Vivo Models for Pathotyping and Vaccine Efficacy for Swine Influenza.
机构信息
Virus and Prion Research Unit, US Department of Agriculture, Agricultural Research Service, National Animal Disease Center, Ames, IA, USA.
出版信息
Methods Mol Biol. 2020;2123:345-351. doi: 10.1007/978-1-0716-0346-8_25.
PMID:32170700
Abstract
Swine influenza is a disease of the respiratory tract caused by influenza A virus (IAV). Experimental inoculation of pigs involves either aerosolization of virus and inhalation or the direct introduction of virus into the upper or lower respiratory tract. This chapter covers methods for experimental IAV infection of pigs and collection of specific samples to study the pathogenesis of swine influenza and vaccine efficacy.
摘要
猪流感是一种由甲型流感病毒（IAV）引起的呼吸道疾病。实验接种猪涉及病毒的气溶胶化和吸入，或病毒直接引入上呼吸道或下呼吸道。本章涵盖了实验性猪流感病毒感染猪和收集特定样本的方法，以研究猪流感的发病机制和疫苗效力。
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