正中神经的剪切波弹性成像：一项力学研究。
Shear wave elastography of the median nerve: A mechanical study.
机构信息
Biomechanics Laboratory and Tendon and Soft Tissue Biology Laboratory, Mayo Clinic Minnesota, Rochester, Minnesota.
Department of Radiology, Mayo Clinic Minnesota, Rochester, Minnesota.
出版信息
Muscle Nerve. 2020 Jun;61(6):826-833. doi: 10.1002/mus.26863. Epub 2020 Apr 7.
BACKGROUND
Shear wave elastography (SWE) shows promise in peripheral neuropathy evaluation but has potential limitations due to tissue size and heterogeneity. We tested SWE sensitivity to elasticity change and the effect of probe position in a median nerve cadaver model.
METHODS
Ten specimens were used to measure median nerve elasticity under increasing loads using SWE and indentation. Measurements were compared using repeated-measures analysis of variance.
RESULTS
Indentation and SWE-based longitudinal nerve elasticity increased with tensile loading (P < .01), showing a similar relationship. Acquisition in a transverse plane showed lower values compared with longitudinal measurements, mostly under higher loads (P = .03), as did postdissection elasticity (P = .02). Elasticity did not change when measured proximal to the carpal tunnel.
CONCLUSIONS
Longitudinal SWE is sensitive to changes in median nerve elasticity. Measuring elasticity of peripheral nerves noninvasively could elucidate intra-neural pathology related to compression neuropathies, and proof to be of added value as a diagnostic or prognostic tool.
背景
剪切波弹性成像（SWE）在外周神经病变评估中具有应用前景，但由于组织大小和异质性，其具有潜在的局限性。我们在正中神经尸体模型中测试了 SWE 对弹性变化的敏感性以及探头位置的影响。
方法
使用 SWE 和压痕法测量了 10 个标本在逐渐增加的负荷下正中神经的弹性。使用重复测量方差分析比较测量结果。
结果
压痕和基于 SWE 的纵向神经弹性随拉伸载荷增加而增加（P <.01），表现出相似的关系。与纵向测量相比，在横切面上采集的数值较低，主要是在较高的载荷下（P =.03），解剖后弹性也较低（P =.02）。在腕管近端测量时，弹性没有变化。
结论
纵向 SWE 对正中神经弹性变化敏感。非侵入性地测量周围神经的弹性可以阐明与压迫性神经病相关的神经内病理学，并有望成为一种有价值的诊断或预后工具。
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