Universidade Federal de Minas Gerais (UFMG), Alameda Álvaro Celso, 175 / 2° Andar. Santa Efigênia. CEP 30.150-260, Belo Horizonte, MG, Brazil.
Universidade De São Paulo (USP), São Paulo, Brazil.
Adv Rheumatol. 2020 Feb 21;60(1):19. doi: 10.1186/s42358-020-0116-2.
Spondyloarthritis is a group of chronic inflammatory systemic diseases characterized by axial and/or peripheral joints inflammation, as well as extra-articular manifestations. The classification axial spondyloarthritis is adopted when the spine and/or the sacroiliac joints are predominantly involved. This version of recommendations replaces the previous guidelines published in May 2013.A systematic literature review was performed, and two hundred thirty-seven studies were selected and used to formulate 29 recommendations answering 15 clinical questions, which were divided into four sections: diagnosis, non-pharmacological therapy, conventional drug therapy and biological therapy. For each recommendation the level of evidence supporting (highest available), the strength grade according to Oxford, and the degree of expert agreement (inter-rater reliability) is informed.These guidelines bring evidence-based information on clinical management of axial SpA patients, including, diagnosis, treatment, and prognosis.
脊柱关节炎是一组以中轴和/或外周关节炎症以及关节外表现为特征的慢性炎症性系统性疾病。当脊柱和/或骶髂关节主要受累时，采用中轴型脊柱关节炎的分类。本版建议取代了 2013 年 5 月发表的上一版指南。进行了系统的文献复习，选择了 237 项研究，并用于制定 29 条建议，回答 15 个临床问题，这些问题分为四个部分：诊断、非药物治疗、常规药物治疗和生物治疗。对于每条建议，均告知了支持（最高可用）的证据水平、根据牛津大学的强度等级以及专家意见（评分者间信度）的程度。这些指南提供了有关中轴型 SpA 患者临床管理的循证信息，包括诊断、治疗和预后。
