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巴西风湿病学会 2020 年银屑病关节炎治疗指南。

Brazilian Society of Rheumatology 2020 guidelines for psoriatic arthritis.

机构信息

Universidade Federal do Rio de Janeiro (UFRJ), Rua Farme de Amoedo, 140/601. Ipanema, Rio de Janeiro, RJ, CEP 22420-020, Brazil.

Universidade Federal Do Rio Grande Do Sul (UFRS), Porto Alegre, Brazil.

出版信息

Adv Rheumatol. 2021 Nov 24;61(1):69. doi: 10.1186/s42358-021-00219-y.

Abstract

Psoriatic arthritis (PsA) is a chronic and systemic immune disease characterized by inflammation of peripheral and/or axial joints and entheses in patients with psoriasis (PsO). Extra-articular and extracutaneous manifestations and numerous comorbidities can also be present. These recommendations replace the previous version published in May 2013. A systematic review of the literature retrieved 191 articles that were used to formulate 12 recommendations in response to 12 clinical questions, divided into 4 sections: diagnosis, non-pharmacological treatment, conventional drug therapy and biologic therapy. These guidelines provide evidence-based information on the clinical management for PsA patients. For each recommendation, the level of evidence (highest available), degree of strength (Oxford) and degree of expert agreement (interrater reliability) are reported.

摘要

银屑病关节炎(PsA)是一种慢性全身性自身免疫性疾病,其特征为银屑病(PsO)患者外周和/或中轴关节及附着点炎症。也可能存在关节外和皮肤外表现以及多种合并症。这些建议取代了 2013 年 5 月发布的上一版本。对文献的系统回顾检索到 191 篇文章,这些文章被用于针对 12 个临床问题制定 12 条建议,分为 4 个部分:诊断、非药物治疗、常规药物治疗和生物治疗。这些指南为 PsA 患者的临床管理提供了循证信息。对于每条建议,都报告了证据水平(最高可用)、强度等级(牛津)和专家一致性程度(评分者间信度)。

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