Lin Nan, Ou Hui-Dan, Xu Qiyan, Jin Yan, Deng Wei, Yao Zi-Jian
School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
School of Metallurgical Engineering, Anhui University of Technology, Maanshan 243032, China.
ACS Omega. 2020 Feb 28;5(9):4636-4645. doi: 10.1021/acsomega.9b04364. eCollection 2020 Mar 10.
A cyclometallated phosphorescent iridium-based probe to detect CN was prepared through a cyanide alcoholize reaction based on the C^N type main ligand and N^N type ancillary ligand (2-phenyl pyridine and 1,10-phenanthroline-5-carboxaldehyde, respectively). The efficient probe exhibited good sensitivity in response to CN in an CHCN and HO (95/5) mixture within a 1.23 μM detection limit. The response of PL is directly in line with the concentration of CN from 0 to 2.0 equiv. The PL investigation of other reactive anions proved the great selectivity to CN. Additionally, upon adding 1.0 equiv. of cyanide, the formation of cyanohydrin was correctly elucidated in H NMR, FT-IR, and mass spectra studies. The conspicuous results indicate that the iridium complex has the potential possibility of application in other biosystems related to CN.
通过基于C^N型主配体和N^N型辅助配体(分别为2-苯基吡啶和1,10-菲咯啉-5-甲醛)的氰化物醇解反应,制备了一种用于检测CN的环金属化磷光铱基探针。该高效探针在CHCN和HO(95/5)混合物中对CN表现出良好的灵敏度,检测限为1.23 μM。PL响应与0至2.0当量的CN浓度直接相关。对其他活性阴离子的PL研究证明了对CN具有高度选择性。此外,在加入1.0当量的氰化物后,通过核磁共振氢谱、傅里叶变换红外光谱和质谱研究正确阐明了氰醇的形成。这些显著结果表明,铱配合物在与CN相关的其他生物系统中具有潜在的应用可能性。