Zanetti R, Rosso S, Faggiano F, Roffino R, Colonna S, Martina G
Registro Tumori Piemonte, Torino, Italia.
Rev Epidemiol Sante Publique. 1988;36(4-5):309-17.
A population based case-control study was conducted in the province of Torino (Northern Italy) where internal migration produced a population with mixed ethnicity and lifestyles. Two hundred and eight cases of histologically confirmed cutaneous malignant melanoma (CMM) and four hundred and sixteen controls were interviewed. Our results gave evidence to the role of skin reaction to the sun (OR 5.0 in men and 2.2 in women) as an indicator of a group at risk. The increased risk of intense and occasional sun exposure as can be inferred from sun exposure during holidays and outdoor sports, has been confirmed (OR 4.1 in men and 2.7 in women). Ethnic differences did not play an important role in our population, women who used oral contraceptives also did not show an increased risk.
在意大利北部的都灵省开展了一项基于人群的病例对照研究，该地区的内部移民造就了一个种族和生活方式多样化的人群。对208例经组织学确诊的皮肤恶性黑色素瘤（CMM）病例和416名对照进行了访谈。我们的研究结果证明，皮肤对阳光的反应（男性比值比为5.0，女性为2.2）可作为风险群体的一个指标。从假期和户外运动中的阳光暴露情况可以推断，强烈和偶尔的阳光暴露会增加患病风险，这一点已得到证实（男性比值比为4.1，女性为2.7）。种族差异在我们的研究人群中未起到重要作用，使用口服避孕药的女性也未表现出患病风险增加。
