Department of Ophthalmology, National University Hospital, Singapore, Singapore.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ocul Immunol Inflamm. 2020 Apr 2;28(3):391-395. doi: 10.1080/09273948.2020.1738501. Epub 2020 Mar 16.
In December 2019, a novel coronavirus (CoV) epidemic, caused by the severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) emerged from China. This virus causes the coronavirus disease 2019 (COVID-19). Since then, there have been anecdotal reports of ocular infection. The ocular implications of human CoV infections have not been widely studied. However, CoVs have been known to cause various ocular infections in animals. Clinical entities such as conjunctivitis, anterior uveitis, retinitis, and optic neuritis have been documented in feline and murine models. In this article, the current evidence suggesting possible human CoV infection of ocular tissue is reviewed. The review article will also highlight animal CoVs and their associated ocular infections. We hope that this article will serve as a start for further research into the ocular implications of human CoV infections.
2019 年 12 月，一种新型冠状病毒（CoV）疫情在中国爆发，由严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）引起。这种病毒导致 2019 年冠状病毒病（COVID-19）。从那时起，就有眼感染的传闻报道。人类 CoV 感染的眼部影响尚未得到广泛研究。然而，已知 CoV 会导致动物的各种眼部感染。在猫和鼠模型中已经记录了临床实体，如结膜炎、前葡萄膜炎、视网膜炎和视神经炎。在本文中，回顾了目前可能存在的人类 CoV 感染眼部组织的证据。综述文章还将重点介绍动物 CoV 及其相关的眼部感染。我们希望这篇文章将为进一步研究人类 CoV 感染的眼部影响提供一个起点。
