冠状病毒：新兴人畜共患病的范例。
Coronaviruses: a paradigm of new emerging zoonotic diseases.
机构信息
Department of Molecular Medicine, University of Padova, Via Gabelli 63, 35121, Padova, Italy.
出版信息
Pathog Dis. 2019 Dec 1;77(9). doi: 10.1093/femspd/ftaa006.
Abstract
A novel type of coronavirus (2019-nCoV) infecting humans appeared in Wuhan, China, at the end of December 2019. Since the identification of the outbreak the infection quickly spread involving in one month more than 31,000 confirmed cases with 638 death. Molecular analysis suggest that 2019-nCoV could be originated from bats after passaging in intermediate hosts, highlighting the high zoonotic potential of coronaviruses.
摘要
一种新型冠状病毒（2019-nCoV）于 2019 年 12 月在中国武汉出现。自疫情爆发以来，感染迅速蔓延，一个月内确诊病例超过 31000 例，死亡 638 例。分子分析表明，2019-nCoV 可能起源于蝙蝠，在中间宿主中传播后，突出了冠状病毒的高人畜共患潜力。
相似文献
1
Coronaviruses: a paradigm of new emerging zoonotic diseases.冠状病毒：新兴人畜共患病的范例。
Pathog Dis. 2019 Dec 1;77(9). doi: 10.1093/femspd/ftaa006.
2
[Source of the COVID-19 pandemic: ecology and genetics of coronaviruses (Betacoronavirus: Coronaviridae) SARS-CoV, SARS-CoV-2 (subgenus Sarbecovirus), and MERS-CoV (subgenus Merbecovirus).].[新冠疫情的源头：冠状病毒（β冠状病毒：冠状病毒科）、严重急性呼吸综合征冠状病毒（SARS-CoV）、严重急性呼吸综合征冠状病毒2（SARS-CoV-2，Sarbecovirus亚属）和中东呼吸综合征冠状病毒（MERS-CoV，Merbecovirus亚属）的生态学与遗传学。]
Vopr Virusol. 2020;65(2):62-70. doi: 10.36233/0507-4088-2020-65-2-62-70.
3
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.新冠病毒的基因组特征和流行病学：对病毒起源和受体结合的影响。
Lancet. 2020 Feb 22;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8. Epub 2020 Jan 30.
4
Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins.鉴定马来穿山甲体内的 SARS-CoV-2 相关冠状病毒
Nature. 2020 Jul;583(7815):282-285. doi: 10.1038/s41586-020-2169-0. Epub 2020 Mar 26.
5
Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments.新型冠状病毒（2019-nCoV）的现状，基于基因组分析的进化视角及最新进展。
Vet Q. 2020 Dec;40(1):68-76. doi: 10.1080/01652176.2020.1727993.
6
Epidemiological Features of the 2019 Novel Coronavirus Outbreak in China.中国 2019 年新型冠状病毒疫情的流行病学特征。
Curr Top Med Chem. 2020;20(13):1137-1140. doi: 10.2174/1568026620999200511094117.
7
The global spread of 2019-nCoV: a molecular evolutionary analysis.2019-nCoV 在全球的传播：分子进化分析。
Pathog Glob Health. 2020 Mar;114(2):64-67. doi: 10.1080/20477724.2020.1725339. Epub 2020 Feb 12.
8
COVID-19: A Worldwide, Zoonotic, Pandemic Outbreak.新型冠状病毒肺炎：一场全球性的人畜共患病大流行疫情。
Altern Ther Health Med. 2020 Aug;26(S2):56-64.
9
2019_nCoV/SARS-CoV-2: rapid classification of betacoronaviruses and identification of Traditional Chinese Medicine as potential origin of zoonotic coronaviruses.2019-nCoV/SARS-CoV-2：贝塔冠状病毒的快速分类和鉴定，以及传统中药作为人畜共患冠状病毒潜在起源的证据。
Lett Appl Microbiol. 2020 May;70(5):342-348. doi: 10.1111/lam.13285. Epub 2020 Feb 28.
10
Where Did SARS-CoV-2 Come From?SARS-CoV-2 从何而来？
Mol Biol Evol. 2020 Sep 1;37(9):2463-2464. doi: 10.1093/molbev/msaa162.
引用本文的文献
1
Convergent evolution of the G3BP1-binding motif in betacoronavirus nucleocapsid proteins.β冠状病毒核衣壳蛋白中G3BP1结合基序的趋同进化。
Virus Evol. 2025 Aug 22;11(1):veaf063. doi: 10.1093/ve/veaf063. eCollection 2025.
2
Analysis of KIR and HLA Polymorphism in Chinese Individuals With COVID-19.分析中国 COVID-19 患者的 KIR 和 HLA 多态性。
HLA. 2024 Oct;104(4):e15715. doi: 10.1111/tan.15715.
3
Comprehensive Insights Into the Multi-faceted Manifestations of COVID-19: A Narrative Review.对新冠病毒病多方面表现的全面洞察：一篇叙述性综述
Cureus. 2024 Jun 30;16(6):e63493. doi: 10.7759/cureus.63493. eCollection 2024 Jun.
4
Screening for SARS-CoV-2 and Other Coronaviruses in Urban Pigeons (Columbiformes) from the North of Spain under a 'One Health' Perspective.从“同一健康”视角对西班牙北部城市家鸽（鸽形目）进行SARS-CoV-2和其他冠状病毒的筛查。
Microorganisms. 2024 Jun 4;12(6):1143. doi: 10.3390/microorganisms12061143.
5
The Potential Role of Viral Persistence in the Post-Acute Sequelae of SARS-CoV-2 Infection (PASC).病毒持续存在在新冠病毒感染后急性后遗症（PASC）中的潜在作用
Pathogens. 2024 May 8;13(5):388. doi: 10.3390/pathogens13050388.
6
Optic Neuritis in Resolving Phase of COVID-19 Infection and Its Management: A Case Report.新冠病毒感染缓解期的视神经炎及其管理：一例报告
Cureus. 2024 Apr 14;16(4):e58257. doi: 10.7759/cureus.58257. eCollection 2024 Apr.
7
COVID-19 and importance of environmental sustainability.新型冠状病毒肺炎与环境可持续性的重要性。
Environ Sustain (Singap). 2020;3(2):117-119. doi: 10.1007/s42398-020-00107-z. Epub 2020 May 13.
8
Effect of a Total Extract and Saponins from L. on Human Coronavirus Replication In Vitro.虎杖总提取物及其单体对人冠状病毒复制的影响。
Int J Mol Sci. 2023 Nov 20;24(22):16525. doi: 10.3390/ijms242216525.
9
Survival Analysis of Hospital Length of Stay of COVID-19 Patients in Ilam Province, Iran: A Retrospective Cross-Sectional Study.伊朗伊拉姆省新冠肺炎患者住院时间的生存分析：一项回顾性横断面研究
J Clin Med. 2023 Oct 23;12(20):6678. doi: 10.3390/jcm12206678.
10
Community-based management of a five-arm randomised clinical trial in COVID-19 outpatients in South Africa: challenges and opportunities.南非 COVID-19 门诊患者五臂随机临床试验的社区管理：挑战与机遇。
Trials. 2023 Oct 4;24(1):635. doi: 10.1186/s13063-023-07577-6.
本文引用的文献
1
Novel coronavirus 2019-nCoV (COVID-19): early estimation of epidemiological parameters and epidemic size estimates.新型冠状病毒 2019-nCoV (COVID-19)：流行病学参数和疫情规模的早期估计。
Philos Trans R Soc Lond B Biol Sci. 2021 Jul 19;376(1829):20200265. doi: 10.1098/rstb.2020.0265. Epub 2021 May 31.
2
Emerging coronaviruses: Genome structure, replication, and pathogenesis.新型冠状病毒：基因组结构、复制与发病机制
J Med Virol. 2020 Oct;92(10):2249. doi: 10.1002/jmv.26234. Epub 2020 Aug 2.
3
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.SARS-CoV-2 及其他 B 属β冠状病毒的细胞进入和受体使用功能评估。
Nat Microbiol. 2020 Apr;5(4):562-569. doi: 10.1038/s41564-020-0688-y. Epub 2020 Feb 24.
4
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.瑞德西韦和氯喹在体外能有效抑制新出现的新型冠状病毒（2019 - 新冠病毒）。
Cell Res. 2020 Mar;30(3):269-271. doi: 10.1038/s41422-020-0282-0. Epub 2020 Feb 4.
5
A pneumonia outbreak associated with a new coronavirus of probable bat origin.一种新型冠状病毒引发的肺炎疫情，该病毒可能来源于蝙蝠。
Nature. 2020 Mar;579(7798):270-273. doi: 10.1038/s41586-020-2012-7. Epub 2020 Feb 3.
6
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.新冠病毒的基因组特征和流行病学：对病毒起源和受体结合的影响。
Lancet. 2020 Feb 22;395(10224):565-574. doi: 10.1016/S0140-6736(20)30251-8. Epub 2020 Jan 30.
7
Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event.对新型冠状病毒（2019-nCoV）的全基因组进化分析否定了其是近期重组事件导致出现的假说。
Infect Genet Evol. 2020 Apr;79:104212. doi: 10.1016/j.meegid.2020.104212. Epub 2020 Jan 29.
8
Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany.德国一名无症状接触者传播2019新型冠状病毒感染
N Engl J Med. 2020 Mar 5;382(10):970-971. doi: 10.1056/NEJMc2001468. Epub 2020 Jan 30.
9
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.新型冠状病毒受体识别：基于 SARS 冠状病毒长达十年结构研究的分析。
J Virol. 2020 Mar 17;94(7). doi: 10.1128/JVI.00127-20.
10
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.新型冠状病毒感染肺炎在中国武汉的早期传播动力学。
N Engl J Med. 2020 Mar 26;382(13):1199-1207. doi: 10.1056/NEJMoa2001316. Epub 2020 Jan 29.
Zotero 插件