Pacific Derm, Vancouver, British Columbia, Canada.
Department of Dermatology & Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
J Cosmet Laser Ther. 2020 Feb 17;22(2):96-99. doi: 10.1080/14764172.2020.1740275. Epub 2020 Mar 16.
Minocycline-induced pigmentation (MIP) is an infrequent complication of minocycline therapy, with four subtypes each with distinct clinical features and histologic staining patterns. MIP may resolve following discontinuation of minocycline therapy or it may persist indefinitely. A 64-year-old Caucasian male presented with a 6 month history of progressive blue-gray facial pigmentation distributed symmetrically over his face. One session utilizing a 755 nm picosecond Alexandrite laser resulted in immediate and significant clearance of the pigment in all treated areas. Long-term follow-up at 2 years revealed no recurrence of the MIP.
米诺环素诱导的色素沉着症（MIP）是米诺环素治疗的一种罕见并发症，有四种亚型，每种亚型都有独特的临床特征和组织学染色模式。MIP 可能在停止米诺环素治疗后消退，也可能无限期持续。一名 64 岁的白人男性，6 个月前出现渐进性蓝灰色面部色素沉着，对称分布于面部。一次 755nm 皮秒亚历山大激光治疗，所有治疗区域的色素立即显著清除。2 年的长期随访未发现 MIP 复发。
