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基于偏振光摄影分析评估755纳米皮秒激光单次治疗消除色素沉着性皮肤病变的疗效

Evaluation of the Efficacy of the 755 nm Picosecond Laser in Eliminating Pigmented Skin Lesions after a Single Treatment Based on Photographic Analysis with Polarised Light.

作者信息

Zawodny Piotr, Wahidi Nicole, Zawodny Paweł, Duchnik Ewa, Stój Elżbieta, Malec Wiola Rozalia, Kulaszyńska Monika, Skonieczna-Żydecka Karolina, Sieńko Jerzy

机构信息

Medical Center Zawodny Clinic, Ku Słońcu 58, 71-047 Szczecin, Poland.

Department of Aesthetic Dermatology, Pomeranian Medical University in Szczecin, Powstancow Wlkp 72, 70-111 Szczecin, Poland.

出版信息

J Clin Med. 2024 Jan 5;13(2):304. doi: 10.3390/jcm13020304.

Abstract

INTRODUCTION

Pigmentary changes can be bothersome and affect one's well-being. Laser therapy has been shown to effectively treat such skin discolouration. We aimed to assess the utility of a 755 nm alexandrite laser in pigmented lesions removal.

MATERIALS AND METHODS

A total of 109 patients aged 44.17 ± 8.2 years were enrolled and underwent laser treatment of facial skin hyperpigmentation. The efficacy was analysed on the basis of photographic diagnosis using the VISIA Complexion Analysis System. The following measures were assessed: (1) score; (2) feature count; (3) comparison figure.

RESULTS

A single laser treatment significantly improved the size and area of the lesion and decreased the number of lesion features. Parallelly, the overall skin condition significantly improved ( < 0.05). We found a statistical tendency of a higher feature count baseline, thus its change in men ( = 0.05 and 0.07, respectively), but failed to find any statistically significant associations ( > 0.05) between tested measures and skin phototypes and hyperpigmentation types. Age was also not correlated with the laser efficacy ( > 0.05).

CONCLUSIONS

The use of the 755 nm laser is effective in reducing pigmented lesions.

摘要

引言

色素沉着变化可能令人烦恼并影响人的健康。激光疗法已被证明能有效治疗此类皮肤色素沉着。我们旨在评估755纳米翠绿宝石激光在去除色素沉着病变方面的效用。

材料与方法

共纳入109例年龄为44.17±8.2岁的患者,对其面部皮肤色素沉着进行激光治疗。使用VISIA肤色分析系统,基于照片诊断分析疗效。评估以下指标:(1)评分;(2)特征计数;(3)对比图。

结果

单次激光治疗显著改善了病变的大小和面积,减少了病变特征数量。同时,整体皮肤状况显著改善(P<0.05)。我们发现男性的特征计数基线有更高的统计学趋势,因此其变化分别为P=0.05和0.07,但未发现测试指标与皮肤光类型和色素沉着类型之间存在任何统计学显著关联(P>0.05)。年龄也与激光疗效无关(P>0.05)。

结论

使用755纳米激光可有效减少色素沉着病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe1e/10816936/0492d4d5a0bc/jcm-13-00304-g001.jpg

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