Celakovská Jarmila, Bukač Josef
Department of Dermatology and Venereology, Medical Faculty of Charles University, Hradec Králové, Czech Republic.
Department of Medical Biophysic, Medical Faculty of Charles University, Hradec Králové, Czech Republic.
Indian J Dermatol. 2014 Sep;59(5):445-50. doi: 10.4103/0019-5154.139867.
A few reports demonstrate the comorbidity of food allergy and allergic march in adult patients.
To evaluate, if there is some relation in atopic dermatitis patients at the age 14 years and older who suffer from food allergy to common food allergens to other allergic diseases and parameters as bronchial asthma, allergic rhinitis, duration of atopic dermatitis, family history and onset of atopic dermatitis.
Complete dermatological and allergological examination was performed; these parameters were examined: food allergy (to wheat flour, cow milk, egg, peanuts and soy), the occurrence of bronchial asthma, allergic rhinitis, duration of atopic dermatitis, family history and onset of atopic dermatitis. The statistical evaluation of the relations among individual parameters monitored was performed.
Food allergy was altogether confirmed in 65 patients (29%) and these patients suffer significantly more often from bronchial asthma and allergic rhinitis. Persistent atopic dermatitis lesions and positive data in family history about atopy are recorded significantly more often in patients with confirmed food allergy to examined foods as well. On the other hand, the onset of atopic dermatitis under 5 year of age is not recorded significantly more often in patients suffering from allergy to examined foods.
Atopic dermatitis patients suffering from food allergy suffer significantly more often from allergic rhinitis, bronchial asthma, persistent eczematous lesions and have positive data about atopy in their family history.
少数报告表明成年患者存在食物过敏与过敏性进程的共病情况。
评估14岁及以上患有对常见食物过敏原过敏的特应性皮炎患者与其他过敏性疾病以及诸如支气管哮喘、过敏性鼻炎、特应性皮炎病程、家族史和特应性皮炎发病之间是否存在某种关联。
进行了全面的皮肤病学和过敏学检查；检查了这些参数：食物过敏（对小麦粉、牛奶、鸡蛋、花生和大豆）、支气管哮喘的发生情况、过敏性鼻炎、特应性皮炎病程、家族史和特应性皮炎发病情况。对所监测的各个参数之间的关系进行了统计学评估。
共65例患者（29%）被确诊存在食物过敏，这些患者患支气管哮喘和过敏性鼻炎的频率明显更高。在对所检查食物确诊存在食物过敏的患者中，持续性特应性皮炎皮损以及家族史中关于特应性的阳性数据记录也明显更多。另一方面，对所检查食物过敏的患者中，5岁以下特应性皮炎发病情况的记录并未明显增多。
患有食物过敏的特应性皮炎患者患过敏性鼻炎、支气管哮喘、持续性湿疹性皮损的频率明显更高，且家族史中有关于特应性的阳性数据。
