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Saliva in the diagnosis of diseases.唾液在疾病诊断中的应用。
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尼日利亚伊巴丹医护人员在临床和实验室检查中对唾液作为样本相较于其他体液的偏好。

Preference of saliva over other body fluids as samples for clinical and laboratory investigations among healthcare workers in Ibadan, Nigeria.

作者信息

Lasisi Taye Jemilat, Lawal Folake Barakat

机构信息

Department of Physiology, University of Ibadan, Ibadan, Nigeria.

Department of Oral Pathology, University of Ibadan and University College Hospital, Ibadan, Nigeria.

出版信息

Pan Afr Med J. 2019 Dec 11;34:191. doi: 10.11604/pamj.2019.34.191.18738. eCollection 2019.

DOI:10.11604/pamj.2019.34.191.18738
PMID:32180865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7060920/
Abstract

INTRODUCTION

The study aimed to assess the knowledge and practices of clinicians and laboratory scientists on the use of saliva for clinical or laboratory tests.

METHODS

This was a cross-sectional survey of health care workers (100 clinicians and 62 laboratory scientists) closely involved with specimen collection for clinical and laboratory investigation at two health facilities (secondary and tertiary) in Nigeria. Information was obtained from participants using pretested structured questionnaires. Data were analyzed with SPSS and level of significance set at p < 5%.

RESULTS

The mean age of the study participants was 34.1 (±6.6) years. The majority (95.7%) knew saliva could be used for clinical/laboratory test. A higher proportion of laboratory scientists knew saliva could be used in diagnosing HIV (59.2%), oral diseases (88.7%), oro-facial tumors (64.4%) and genetic testing (94.5%) compared to (41%), (80%), (40%) and (80%), of clinicians respectively (p < 0.05). More clinicians (85%) indicated saliva as a good specimen for diagnosing systemic diseases compared with scientists (63%), p < 0.001. Saliva was the most comfortable/convenient body fluid to obtain from patients with more clinicians (80%) mentioning this than scientists (49.1%), p < 0.001. Twenty-six clinicians had used saliva for disease diagnosis (64%), treatment monitoring (28%) or research purposes (8%). Saliva sampling for research purposes was more prevalent among clinicians (p = 0.004).

CONCLUSION

The majority of the health care workers knew the various uses and advantages of saliva as a specimen for clinical and laboratory investigation. However, few indicated previous use for clinical and laboratory investigation especially in the area of research.

摘要

引言

本研究旨在评估临床医生和实验室科学家在使用唾液进行临床或实验室检测方面的知识和实践情况。

方法

这是一项对医疗工作者(100名临床医生和62名实验室科学家)的横断面调查,这些人员在尼日利亚的两家医疗机构(二级和三级)密切参与临床和实验室检查的标本采集工作。通过使用预先测试的结构化问卷从参与者那里获取信息。数据用SPSS进行分析,显著性水平设定为p < 5%。

结果

研究参与者的平均年龄为34.1(±6.6)岁。大多数人(95.7%)知道唾液可用于临床/实验室检测。与临床医生分别为41%、80%、40%和80%相比,更高比例的实验室科学家知道唾液可用于诊断艾滋病毒(59.2%)、口腔疾病(88.7%)、口腔颌面肿瘤(64.4%)和基因检测(94.5%)(p < 0.05)。与科学家(63%)相比,更多临床医生(85%)认为唾液是诊断全身性疾病的良好标本,p < 0.001。唾液是从患者身上获取的最舒适/方便的体液,提及这一点的临床医生(80%)比科学家(49.1%)更多,p < 0.001。26名临床医生曾将唾液用于疾病诊断(64%)、治疗监测(28%)或研究目的(8%)。临床医生中出于研究目的进行唾液采样更为普遍(p = 0.004)。

结论

大多数医疗工作者了解唾液作为临床和实验室检查标本的各种用途和优势。然而,很少有人表示之前曾将其用于临床和实验室检查,尤其是在研究领域。