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拉合尔马纳瓦地区人群中酸相关性疾病自我药疗的患病率

Prevalence of Self-medication for Acid Peptic Disease amongst People of Manawa, Lahore.

作者信息

Chattha Irsa R, Zaffar Sehrish, Tariq Shoaib, Siddiqui Waqar Ahmed, Zaman Kamran, Kamran Rizwana, Talat Aisha, Tanveer Hira

机构信息

Pharmacology, CMH Lahore Medical College (NUMS), Lahore, PAK.

Internal Medicine, Indus Hospital Manawan, Lahore, PAK.

出版信息

Cureus. 2020 Jan 30;12(1):e6817. doi: 10.7759/cureus.6817.

DOI:10.7759/cureus.6817
PMID:32181064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7051106/
Abstract

Introduction Acid peptic disease is a common disorder, affecting millions of people worldwide. Its pharmacological management includes proton pump inhibitors, H blockers, antacids and mucosal protective agents. Multiple studies in Pakistan have shown increased tendency of population for self-medication. This has serious implications regarding false diagnoses, misuse of drugs and occurrence of adverse effects. The objective of this study was to estimate the prevalence of self-medication among the people of Manawa, Lahore. Methods A cross-sectional study was conducted between January 2019 and June 2019 amongst the general population of Manawa, Lahore. Patients with the typical presentation of acid peptic disease were included in the study. A total of 500 people, fulfilling the inclusion criteria, were chosen. A questionnaire form was adapted from similar studies performed on self-medication. It was divided into two parts. First part included the social and demographic data while the second part consisted of details about the prevalence and factors related to the practice of self-medication amongst acid peptic disease (APD) patients. The data collected was transcribed into SPSS 22.0 (IBM Corp., Armonk, NY) for statistical analysis. All the categorical variables were analyzed as frequencies and percentages. No statistical comparisons were done as it was a descriptive, exploratory study. Results Out of 500 participants, 404 were females and 96 were males. Most of them were middle-aged (53%) and illiterate (68.4%). Number of participants who practiced self-medication was found to be 313 (62.6%). The highest prevalence of self-medication was found for proton pump inhibitors (43.1%), followed by antacids (23.6%), unknown homeopathic and Hakeem medicine (20.4%) and H blockers (12.8%). The most common reasons stated for self-medication included inability to afford medical consultation (44.2%), lack of knowledge about drug side effects (35.8%), easy access to Hakeem and homeopathic medicines (27.6% and 4.8%, respectively) and inaccessibility to doctors (19.2%). Conclusion A large majority of people in Manawa practise self-medication for acid peptic disease, owing to multiple reasons.

摘要

引言 酸相关性疾病是一种常见病症,全球数以百万计的人受其影响。其药物治疗包括质子泵抑制剂、H受体阻滞剂、抗酸剂和黏膜保护剂。巴基斯坦的多项研究表明,民众自我药疗的倾向有所增加。这在误诊、药物滥用和不良反应发生方面具有严重影响。本研究的目的是估计拉合尔马纳瓦地区民众自我药疗的患病率。

方法 2019年1月至2019年6月期间,在拉合尔马纳瓦地区的普通人群中进行了一项横断面研究。具有酸相关性疾病典型表现的患者被纳入研究。总共选择了500名符合纳入标准的人。问卷形式改编自以往关于自我药疗的类似研究。问卷分为两部分。第一部分包括社会和人口统计学数据,第二部分包括酸相关性疾病(APD)患者自我药疗的患病率及相关因素的详细信息。收集到的数据被录入SPSS 22.0(IBM公司,纽约州阿蒙克)进行统计分析。所有分类变量均按频率和百分比进行分析。由于这是一项描述性探索性研究,未进行统计比较。

结果 在500名参与者中,404名是女性,96名是男性。他们大多为中年人(53%)且文盲率为(68.4%)。发现进行自我药疗的参与者有313人(62.6%)。自我药疗患病率最高的是质子泵抑制剂(43.1%),其次是抗酸剂(23.6%)、不明顺势疗法和哈基姆药物(20.4%)以及H受体阻滞剂(12.8%)。自我药疗最常见的原因包括负担不起医疗咨询费用(44.2%)、对药物副作用缺乏了解(35.8%)、容易获得哈基姆和顺势疗法药物(分别为27.6%和4.8%)以及无法看医生(19.2%)。

结论 由于多种原因,马纳瓦地区的绝大多数人对酸相关性疾病进行自我药疗。

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