Hlashwayo Delfina Fernandes, Sigaúque Betuel, Bila Custódio Gabriel
Department of Biological Sciences, Faculty of Sciences, Eduardo Mondlane University, Maputo, Mozambique.
Faculty of Veterinary Science, Eduardo Mondlane University, Maputo, Mozambique.
Heliyon. 2020 Mar 9;6(3):e03537. doi: 10.1016/j.heliyon.2020.e03537. eCollection 2020 Mar.
Low sanitary conditions characterize the rural and urban households in Sub-Saharan African region. Those environmental conditions propitiate the transmission of bacterial infections between animals and humans. spp. is a zoonotic bacterium and cause of human gastroenteritis worldwide, whose main symptom is diarrhea. It is normally found in the digestive tract of many farm animals as a commensal but some species cause diseases in animals. It is important to understand the occurrence of these bacteria in animals, as they may also play a role in transmission to humans. The main objective of this review was to describe the prevalence of in animals in Sub-Saharan Africa. We also report findings on antibiotic resistance.
We followed PRISMA guidelines to find studies about occurrence of spp. in animals in all countries from Sub-Saharan Africa. PubMed, Cochrane Library, CINAHL, African Index Medicus, African Journals Online, Google Scholar and Science Direct were searched for studies published between 2000 and 2019.
We found 70 studies that described occurrence of spp. in animals in 18 out of 53 countries of Sub-Saharan Africa. and were the predominant species isolated. The majority of studies were found in Western Africa. Middle Africa had the lowest amount of data. Most records presented data from Nigeria (n = 25), South Africa (n = 14) and Tanzania (n = 11). Cattle and chickens appear to be important hosts and may be playing an important role in transmitting to humans. Most isolates were resistant to erythromycin (44%), ampicillin (39%), tetracycline (33%), nalidixic acid (31%) and ciprofloxacin (30%).
Several studies about spp. in animals have been published in the last 19 years but information on the epidemiology of campylobacteriosis is scarce in most Sub-Saharan African countries. Antibiotic resistance is an increasing concern in many countries. Measures should be taken to prevent infection by this pathogen in the region and to control antibiotic resistance.
卫生条件差是撒哈拉以南非洲地区农村和城市家庭的特征。这些环境条件促使细菌在动物和人类之间传播。弯曲杆菌属是一种人畜共患细菌，是全球人类肠胃炎的病因，其主要症状是腹泻。它通常作为共生菌存在于许多农场动物的消化道中，但有些种类会导致动物患病。了解这些细菌在动物中的存在情况很重要，因为它们也可能在传播给人类的过程中发挥作用。本综述的主要目的是描述撒哈拉以南非洲地区动物中弯曲杆菌属的流行情况。我们还报告了关于抗生素耐药性的研究结果。
我们遵循PRISMA指南，查找撒哈拉以南非洲所有国家动物中弯曲杆菌属发生情况的研究。在PubMed、考克兰图书馆、护理学与健康领域数据库、非洲医学索引、非洲在线期刊、谷歌学术和科学Direct上搜索2000年至2019年发表的研究。
我们发现70项研究描述了撒哈拉以南非洲53个国家中18个国家动物中弯曲杆菌属的发生情况。空肠弯曲杆菌和结肠弯曲杆菌是分离出的主要菌种。大多数研究来自西非。中非的数据量最少。大多数记录提供了尼日利亚（n = 25）、南非（n = 14）和坦桑尼亚（n = 11）的数据。牛和鸡似乎是重要宿主，可能在传播给人类方面发挥重要作用。大多数弯曲杆菌分离株对红霉素（44%）、氨苄青霉素（39%）、四环素（33%）、萘啶酸（31%）和环丙沙星（30%）耐药。
在过去19年里已经发表了几项关于动物中弯曲杆菌属的研究，但大多数撒哈拉以南非洲国家关于弯曲杆菌病流行病学的信息很少。抗生素耐药性在许多国家日益受到关注。应采取措施预防该地区这种病原体的感染并控制抗生素耐药性。
