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髋关节置换术后手术入路与主要手术并发症的关系。

Association Between Surgical Approach and Major Surgical Complications in Patients Undergoing Total Hip Arthroplasty.

机构信息

Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

Sunnybrook Health Sciences Centre, Division of Orthopaedic Surgery, Toronto, Ontario, Canada.

出版信息

JAMA. 2020 Mar 17;323(11):1070-1076. doi: 10.1001/jama.2020.0785.

Abstract

IMPORTANCE

Controversy exists about the preferred surgical approach for total hip arthroplasty (THA).

OBJECTIVE

To determine whether an anterior approach is associated with lower risk of complications than either a lateral or posterior approach.

DESIGN, SETTING, AND PARTICIPANTS: Population-based retrospective cohort study of all adults in Ontario, Canada, who had undergone primary THA for osteoarthritis between April 1, 2015, and March 31, 2018. All patients were followed up over a 1-year period (study end date, March 31, 2019).

EXPOSURES

Surgical approach (anterior vs lateral/posterior) for THA.

MAIN OUTCOMES AND MEASURES

Major surgical complications within 1 year (composite of deep infection requiring surgery, dislocation requiring closed or open reduction, or revision surgery). Outcomes were compared among propensity-score matched groups using Cox proportional hazards regression.

RESULTS

Of the 30 098 patients (mean [SD] age, 67 years [10.7 years]; 16 079 women [53.4%]) who underwent THA, 2995 (10%) underwent the anterior approach; 21 248 (70%), the lateral approach; and 5855 (20%) the posterior approach performed at 1 of 73 hospitals by 1 of 298 surgeons. All patients were followed up for 1 year. Compared with those undergoing the lateral or posterior approach, patients undergoing an anterior approach were younger (mean age, 65 vs 67 years; standardized difference, 0.17); had lower rates of morbid obesity (4.8% vs 7.6%; standardized difference, 0.12), diabetes (14.2% vs 19.9%; standardized difference, 0.15), and hypertension (53.4% vs 62.9%; standardized difference, 0.19); and were treated by higher-volume surgeons (median range, 111 procedures; interquartile range, 69-172 vs 77 procedures, interquartile range, 50-119 in the prior year; standardized difference, 0.55). Compared with 2993 propensity-score matched patients undergoing a lateral or posterior approach, the 2993 matched patients undergoing anterior approaches had a significantly greater risk of a major surgical complication (61 patients [2%] vs 29 patients [1%]; absolute risk difference, 1.07%; 95% CI, 0.46%-1.69%; hazard ratio, 2.07; 95% CI, 1.48 to 2.88).

CONCLUSIONS AND RELEVANCE

Among patients undergoing total hip arthroplasty, an anterior surgical approach compared with a posterior or lateral surgical approach was associated with a small but statistically significant increased risk of major surgical complications. The findings may help inform decisions about surgical approach for hip arthroplasty, although further research is needed to understand pain and functional outcomes.

摘要

重要性

全髋关节置换术(THA)的首选手术入路存在争议。

目的

确定前路是否比侧方或后方入路更能降低并发症风险。

设计、地点和参与者:这是一项基于人群的回顾性队列研究,纳入了 2015 年 4 月 1 日至 2018 年 3 月 31 日期间安大略省所有因骨关节炎接受初次 THA 的成年人。所有患者均随访 1 年(研究截止日期为 2019 年 3 月 31 日)。

暴露因素

THA 的手术入路(前路与侧方/后方)。

主要结果和测量指标

1 年内的主要手术并发症(复合结局为深部感染需要手术、脱位需要闭合或开放复位或翻修手术)。采用 Cox 比例风险回归比较倾向评分匹配组之间的结果。

结果

在 30988 例(平均[标准差]年龄,67 岁[10.7 岁];16079 例女性[53.4%])接受 THA 的患者中,2995 例(10%)采用前路;21248 例(70%)采用侧方入路;5855 例(20%)采用后方入路,在 73 家医院中的 1 家由 298 名外科医生中的 1 名进行。所有患者均随访 1 年。与接受侧方或后方入路的患者相比,接受前路入路的患者更年轻(平均年龄,65 岁 vs 67 岁;标准化差异,0.17);病态肥胖的发生率较低(4.8% vs 7.6%;标准化差异,0.12)、糖尿病(14.2% vs 19.9%;标准化差异,0.15)和高血压(53.4% vs 62.9%;标准化差异,0.19);由更高容量的外科医生进行治疗(中位数范围,111 例;四分位距,69-172 比 77 例,前一年的四分位距,50-119;标准化差异,0.55)。与 2993 例匹配的接受侧方或后方入路的倾向性评分患者相比,2993 例匹配的接受前路入路的患者发生主要手术并发症的风险显著更高(61 例[2%] vs 29 例[1%];绝对风险差异,1.07%;95%CI,0.46%-1.69%;风险比,2.07;95%CI,1.48 至 2.88)。

结论和相关性

在接受全髋关节置换术的患者中,前路手术与后路或侧方手术相比,主要手术并发症的风险略有但具有统计学意义的增加。这些发现可能有助于告知髋关节置换术的手术入路决策,尽管需要进一步研究以了解疼痛和功能结局。

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