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评估加权鉴别力计算在辅助选择用于药物分析的色谱系统方面的作用。

Evaluation of weighted discriminating power calculations as an aid to the selection of chromatographic systems for the analyses of drugs.

作者信息

Moffat A C, Owen P, Brown C

出版信息

J Chromatogr. 1978 Nov 21;161:179-85. doi: 10.1016/s0021-9673(01)85225-0.

Abstract

In toxicological analyses some chromatographic separations are more important than others. Two weighting methods for chromatographic data are described which incorporate the importance of particular separations into discriminating power calculations. The data were abstracted from a publication on the separations of acidic drugs on thin-layer chromatographic systems. When compared with non-weighted discriminating power calculations, those obtained with the weighting procedure did not give any advantage.

摘要

在毒理学分析中,某些色谱分离比其他分离更为重要。本文描述了两种色谱数据加权方法,这些方法将特定分离的重要性纳入鉴别能力计算中。数据摘自一篇关于酸性药物在薄层色谱系统上分离的出版物。与未加权的鉴别能力计算相比,采用加权程序获得的结果没有任何优势。

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引用本文的文献

1
[Computer-assisted identification of basic substances].
Z Rechtsmed. 1987;98(4):249-54. doi: 10.1007/BF00201231.

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