Department of Internal Medicine, Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Int J Chron Obstruct Pulmon Dis. 2020 Mar 3;15:501-514. doi: 10.2147/COPD.S231317. eCollection 2020.
BACKGROUND AND AIM: Although air pollution is a serious problem in Ahvaz, the association between air pollution and respiratory diseases has not been studied enough in this area. The aim of this study was to determine the relation between short-term exposure to air pollutants and the risk of hospital admissions due to asthma, COPD, and bronchiectasis in Ahvaz. METHODS: Hospital admissions data and air pollutants including O, NO, NO, SO, CO, PM and PM were obtained from 2008 to 2018. Adjusted Quasi-Poisson regression with a distributed lag model, controlled for trend, seasonality, weather, weekdays, and holidays was used for data analysis. RESULTS: The results showed a significant increase in hospital admissions for asthma (RR=1.004, 95% CI: 1.002-1.007) and COPD (RR=1.003, 95% CI: 1.001-1.005) associated with PM. PM was associated with increased hospital admissions due to bronchiectasis in both genders (Men: RR=1.003, 95% CI: 1.001-1.006) (Female: RR=1.003, 95% CI: 1.000-1.006). NO was also associated with an increased risk of hospital admissions for asthma (RR=1.040, 95% CI: 1.008-1.074) and COPD (RR=1.049, 95% CI: 1.010-1.090). SO was associated with the risk of hospital admissions of asthma (RR=1.069, 95% CI: 1.017-1.124) and bronchiectasis (RR=1.030, 95% CI: 1.005-1.056). Finally, CO was associated with COPD (RR=1.643, 95% CI: 1.233-2.191) and bronchiectasis (RR=1.542, 95% CI: 1.035-2.298) hospital admissions. CONCLUSION: Short-term exposure to air pollutants significantly increases the risk of hospital admissions for asthma, COPD, and bronchiectasis in the adult and elderly population.
背景与目的:尽管空气污染是阿瓦士的一个严重问题,但在该地区,空气污染与呼吸道疾病之间的关联尚未得到充分研究。本研究的目的是确定短期暴露于空气污染物与阿瓦士因哮喘、COPD 和支气管扩张症住院的风险之间的关系。
方法:从 2008 年到 2018 年,获得了医院入院数据和包括 O、NO、NO、SO、CO、PM 和 PM 在内的空气污染物数据。使用具有分布滞后模型的调整准泊松回归,控制趋势、季节性、天气、工作日和节假日进行数据分析。
结果:结果表明,与 PM 相关的哮喘(RR=1.004,95%CI:1.002-1.007)和 COPD(RR=1.003,95%CI:1.001-1.005)住院人数显著增加。PM 与两性(男性:RR=1.003,95%CI:1.001-1.006)(女性:RR=1.003,95%CI:1.000-1.006)支气管扩张症住院人数增加有关。NO 也与哮喘(RR=1.040,95%CI:1.008-1.074)和 COPD(RR=1.049,95%CI:1.010-1.090)的住院风险增加有关。SO 与哮喘(RR=1.069,95%CI:1.017-1.124)和支气管扩张症(RR=1.030,95%CI:1.005-1.056)的住院风险有关。最后,CO 与 COPD(RR=1.643,95%CI:1.233-2.191)和支气管扩张症(RR=1.542,95%CI:1.035-2.298)住院有关。
结论:短期暴露于空气污染物会显著增加成人和老年人哮喘、COPD 和支气管扩张症的住院风险。
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