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Neuronal and behavioural consequences of chemical inflammation of rat urinary bladder.

作者信息

McMahon S B

机构信息

St. Thomas' Hospital Medical School, London, UK.

出版信息

Agents Actions. 1988 Dec;25(3-4):231-3. doi: 10.1007/BF01965020.

DOI:10.1007/BF01965020
PMID:3218599
Abstract

Exposure of the urinary bladder of rats to chemical irritants such as turpentine produces a long lasting inflammatory response. Chemosensitive primary afferent fibres supplying the bladder are excited by the irritants. Dorsal horn cells in L6, S1 are also excited, and show slowly developing and persistent increases in ongoing activity, responses to electrical stimulation of vesical afferents and distension of the bladder. These changes may provide an explanation for the sensory and reflex disturbances that occur in cystitis in man.

摘要

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Neurosci Lett. 1984 Dec 21;52(3):235-40. doi: 10.1016/0304-3940(84)90167-8.
2
A model for the study of visceral pain states: chronic inflammation of the chronic decerebrate rat urinary bladder by irritant chemicals.一种用于研究内脏痛状态的模型：通过刺激性化学物质诱导慢性去大脑大鼠膀胱慢性炎症。
Pain. 1987 Jan;28(1):109-127. doi: 10.1016/0304-3959(87)91065-7.
3
Plasma extravasation in the rat urinary bladder following mechanical, electrical and chemical stimuli: evidence for a new population of chemosensitive primary sensory afferents.
急性膀胱炎症对大鼠脊髓内脏伤害性神经元产生差异影响。
Neurosci Lett. 2009 Dec 25;467(2):150-4. doi: 10.1016/j.neulet.2009.10.027. Epub 2009 Oct 12.
4
Lipopolysaccharide-induced upregulation of tumor necrosis factor-alpha (TNF-alpha) in rat spinal cord.
Inflammation. 2008 Oct;31(5):336-43. doi: 10.1007/s10753-008-9083-1.
5
Rostral ventral medulla modulation of the visceromotor reflex evoked by urinary bladder distension in female rats.雌性大鼠膀胱扩张诱发的内脏运动反射的延髓腹侧头端调制
J Pain. 2008 Oct;9(10):920-6. doi: 10.1016/j.jpain.2008.05.011. Epub 2008 Jul 10.
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Neurochem Res. 2009 Feb;34(2):333-41. doi: 10.1007/s11064-008-9780-z. Epub 2008 Jul 10.
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Inflammation-induced enhancement of the visceromotor reflex to urinary bladder distention: modulation by endogenous opioids and the effects of early-in-life experience with bladder inflammation.炎症诱导的膀胱扩张内脏运动反射增强：内源性阿片类物质的调节作用以及早期膀胱炎症经历的影响
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4
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Agents Actions. 1988 Dec;25(3-4):219-21. doi: 10.1007/BF01965016.