Department of Obstetrics and Gynecology, Affiliated Hospital, Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China.
Department of Gynecology, Second Affiliated Hospital, Liaoning University of Traditional Chinese Medicine, Shenyang 110034, China.
J Tradit Chin Med. 2019 Apr;39(2):237-245.
To observe the effect of herb-partitioned moxibustion (HPM) for primary dysmenorrhea.
Six hundred and forty patients were randomized assigned (1∶1) to HPM group and control group. Duration of treatment was 3 months with 3 month follow-up. The primary outcome was pain relief measured by visual analogue scale (VAS). The second outcomes were Cox Menstrual Symptom Scale (CMSS), menstrual pain duration and frequency of analgesics usage. The exploratory outcome included quality of life, RESULTS: After the 3-month treatment and follow-ups, the pain intensity measured by VAS was significantly reduced in both groups compared with baseline (P < 0.05), and it was significantly decreased in HPM group than that of control group (P < 0.001). The higher proportion of participants in the HPM group had a decrease of at least 50% in VAS at the end of treatment, as compared with the control group (P < 0.001). At the 3rd and 6th month, the menstrual pain duration, CMSS score and frequency of analgesics usage in HPM group were significantly lower than those of control group (P < 0.05). After 3 month treatment and follow-ups,the scores of physical, psychological, social and environmental domains were significantly increased than baseline in both groups (P < 0.05), and the sores of physical, psychological and environmental domains were significantly higher in HPM group than those of control group (P < 0.05) .
Herb-partitioned moxibustion reduced menstrual pain and improved quality of life, these were sustained for up to 3 months after treatment. Further research is needed to understand long term effect and the mechanism of the intervention.
观察隔药灸治疗原发性痛经的疗效。
将 640 例患者按 1∶1 随机分为隔药灸组和对照组。治疗时间为 3 个月，随访 3 个月。主要结局指标为视觉模拟评分法（VAS）测量的疼痛缓解程度。次要结局指标为 Cox 月经症状量表（CMSS）、痛经持续时间和镇痛药使用频率。探索性结局指标包括生活质量。
治疗 3 个月及随访结束时，两组 VAS 评分均较基线显著降低（P<0.05），隔药灸组 VAS 评分显著低于对照组（P<0.001）。治疗结束时，隔药灸组 VAS 评分至少降低 50%的患者比例明显高于对照组（P<0.001）。治疗 3 个月及随访结束时，隔药灸组痛经持续时间、CMSS 评分和镇痛药使用频率均明显低于对照组（P<0.05）。治疗 3 个月及随访结束时，两组生理、心理、社会和环境领域评分均较基线显著升高（P<0.05），隔药灸组生理、心理和环境领域评分均明显高于对照组（P<0.05）。
隔药灸可减轻痛经程度，提高生活质量，且疗效可持续 3 个月以上。需要进一步研究以了解该干预措施的长期效果和作用机制。
