Emerg Infect Dis. 2020 Apr;26(4):738-743. doi: 10.3201/eid2604.191476.
Mosquitoborne diseases (e.g., malaria, dengue, and chikungunya) are endemic to India and pose diagnostic challenges during pregnancy. We evaluated an intensified short symptom screening program in India to diagnose dengue during pregnancy. During October 2017-January 2018, we screened pregnant women during antenatal surveillance for symptoms of mosquitoborne diseases (fever only, fever with conjunctivitis, fever with rash, or all 3 symptoms) within the previous 15 days. Of 5,843 pregnant women screened, 52 were enrolled and tested for dengue, chikungunya, and Zika viruses by using a Trioplex real-time reverse transcription PCR. Of 49 who had complete results, 7 (14%) were dengue positive. Of these ocular pain was seen in 4 (57%) and conjunctivitis in 7 (100%). Intensified symptom screening using conjunctivitis, in addition to rash, in pregnant women with fever might improve dengue case detection and can be included in routine symptom screening during pregnancy.
蚊媒疾病（例如疟疾、登革热和基孔肯雅热）在印度流行，给妊娠期的诊断带来了挑战。我们评估了印度加强的短期症状筛查方案，以在妊娠期诊断登革热。在 2017 年 10 月至 2018 年 1 月期间，我们在产前监测期间筛查了出现蚊媒疾病症状（仅发热、发热伴结膜炎、发热伴皮疹或所有 3 种症状）的孕妇，这些症状在过去 15 天内出现过。在筛查的 5843 名孕妇中，有 52 名入组并接受了登革热、基孔肯雅热和寨卡病毒的检测，采用 Trioplex 实时逆转录聚合酶链反应法。在完成检测的 49 名孕妇中，有 7 名（14%）登革热阳性。其中 4 名（57%）出现眼痛，7 名（100%）出现结膜炎。在发热的孕妇中，除皮疹外，若使用结膜炎进行强化症状筛查，可能会提高登革热病例检出率，可将其纳入妊娠期常规症状筛查。
