Emerg Infect Dis. 2020 Apr;26(4):682-691. doi: 10.3201/eid2604.190435.
In 2017, a dengue epidemic of unexpected magnitude occurred in Sri Lanka. A total of 186,101 suspected cases and 440 dengue-related deaths occurred. We conducted a comprehensive analysis of this epidemic by comparing national surveillance data for 2017 with data from the preceding 5 years. In all Sri Lanka districts, dengue incidence in 2017 increased significantly over incidence during the previous 5 years. Older schoolchildren and young adults were more clinically symptomatic than those at extremes of age. Limited virologic surveillance showed the dominant circulating variant was dengue virus type 2 cosmopolitan genotype in the most affected district. One quarter of total annual cases were reported 5 weeks after the southwest monsoon started. Changes in vector abundance were not predictive of the increased incidence. Direct government expenditures on dengue control activities in 2017 were US $12.7 million. The lessons learned from this outbreak are useful for other tropical nations facing increasing dengue incidence.
2017 年，斯里兰卡发生了一场规模空前的登革热疫情。共有 186101 例疑似病例和 440 例与登革热相关的死亡病例。我们通过将 2017 年的国家监测数据与前 5 年的数据进行比较，对此次疫情进行了全面分析。在斯里兰卡所有地区，2017 年的登革热发病率均明显高于前 5 年的发病率。年龄较大的学童和年轻成年人比年龄较小或较大的人临床表现更为明显。有限的病毒学监测表明，在受灾最严重的地区，流行的变异株是登革热病毒 2 型世界性基因型。25%的全年病例是在西南季风开始后的第 5 周报告的。病媒丰度的变化并不能预测发病率的增加。2017 年，政府直接用于登革热控制活动的支出为 1270 万美元。从此次疫情中吸取的经验教训，对其他面临登革热发病率上升的热带国家很有用。
