Müller-Ortiz Hans, Pedreros-Rosales Cristian, Vera-Calzaretta Aldo, González-Burboa Alexis, Zúñiga-San Martín Carlos, Oliveros-Romero María Soledad
Unidad Docente Asistencial, Hospital Las Higueras, Universidad de Concepción, Talcahuano, Chile.
Unidad Paciente Crítico Adulto, Hospital Las Higueras, Talcahuano, Chile.
Rev Med Chil. 2019 Nov;147(11):1443-1448. doi: 10.4067/S0034-98872019001101443.
Chronic kidney disease is associated with an increase in cardiovascular risk and mortality, and a decrease in the health-related quality of life. It is known that the physical capacity of patients with chronic kidney disease is lower than their healthy counterparts. It also decreases progressively after the start of hemodialysis, even leading to the loss of functional independence. There is a positive association between exercise and improvement of many targets in chronic kidney disease, especially in dialysis patients, such as cellular apoptosis, immune improvement and inflammation. In addition, several clinical studies and systematic reviews show an improvement in different clinical and laboratory variables and suggest a lower mortality, proving a reduction of health care economic costs. Exercise intervention in dialysis is safe. Although different guidelines promote exercise, it is necessary to work on its implementation on a large scale.
慢性肾脏病与心血管风险增加、死亡率上升以及健康相关生活质量下降有关。众所周知，慢性肾脏病患者的身体能力低于健康同龄人。在开始血液透析后，其身体能力也会逐渐下降，甚至导致功能独立性丧失。运动与慢性肾脏病诸多指标的改善之间存在正相关，尤其是在透析患者中，如细胞凋亡、免疫改善和炎症等方面。此外，多项临床研究和系统评价显示，不同的临床和实验室指标有所改善，并提示死亡率降低，这证明了医疗保健经济成本的降低。透析中的运动干预是安全的。尽管不同的指南都提倡运动，但仍有必要大力推动其实施。
