El-Bialy Tarek, Farouk Khaled, Carlyle Terry D, Wiltshire William, Drummond Robert, Dumore Tim, Knowlton Kevin, Tompson Bryan
Division of Orthodontics, Katz Group Centre for Pharmacy and Health Research, School of Dentistry, University of Alberta, Edmonton, AB T6G 1C9, Canada.
Department of Orthodontics, Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt.
J Clin Med. 2020 Mar 16;9(3):804. doi: 10.3390/jcm9030804.
The aim of this study was to evaluate the possible effect of low intensity pulsed ultrasound (LIPUS) on tooth movement and root resorption in orthodontic patients. Twenty-one patients were included in a split-mouth study design (group 1). Ten additional patients were included with no LIPUS device being used and this group was used as the negative control group (group 2). Group 1 patients were given LIPUS devices that were randomly assigned to right or left side on upper or lower arches. LIPUS was applied to the assigned side that was obtained by randomization, using transducers that produce ultrasound with a pulse frequency of 1.5 MHz, a pulse repetition rate of 1 kHz, and average output intensity of 30 mW/cm. Cone-beam computed tomography (CBCT) images were taken before and after treatment. The extraction space dimensions were measured every four weeks and root lengths of canines were measured before and after treatment. The data were analyzed using paired -test. The study outcome showed that the mean rate of tooth movement in LIPUS side was 0.266 ± 0.092 mm/week and on the control side was 0.232 ± 0.085 mm/week and the difference was statistically significant. LIPUS increased the rate of tooth movement by an average of 29%. For orthodontic root resorption, the LIPUS side (0.0092 ± 0.022 mm/week) showed a statistically significant decrease as compared to control side (0.0223 ± 0.022 mm/week). The LIPUS application accelerated tooth movement and minimized orthodontically induced tooth root resorption at the same time.
本研究的目的是评估低强度脉冲超声（LIPUS）对正畸患者牙齿移动和牙根吸收的可能影响。21名患者纳入了一项半口研究设计（第1组）。另外纳入10名未使用LIPUS设备的患者，该组用作阴性对照组（第2组）。第1组患者被给予LIPUS设备，随机分配到上牙弓或下牙弓右侧或左侧。使用产生频率为1.5MHz、脉冲重复频率为1kHz、平均输出强度为30mW/cm超声的换能器，将LIPUS应用于通过随机化获得的指定侧。在治疗前后拍摄锥形束计算机断层扫描（CBCT）图像。每四周测量拔牙间隙尺寸，并在治疗前后测量尖牙牙根长度。使用配对t检验分析数据。研究结果表明，LIPUS侧牙齿移动的平均速率为0.266±0.092mm/周，对照组为0.232±0.085mm/周，差异具有统计学意义。LIPUS使牙齿移动速率平均提高了29%。对于正畸牙根吸收，LIPUS侧（0.0092±0.022mm/周）与对照组（0.0223±0.022mm/周）相比，有统计学意义的降低。LIPUS的应用加速了牙齿移动，同时使正畸诱导的牙根吸收最小化。
