Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
University of Toronto, Toronto, Ontario, Canada.
Int J Surg Pathol. 2020 Oct;28(7):700-710. doi: 10.1177/1066896920913110. Epub 2020 Mar 18.
Tissue contaminants in anatomical pathology are not uncommon. While issues related to the presence of extraneous tissue on glass slides are often easily resolved, this is not always the case and several factors may contribute to diagnostic difficulty. Because of this, familiarity with the different steps involved in handling specimens in the anatomical pathology laboratory is essential when troubleshooting possible cross-contaminants. Most commonly, the specimen constituting the source of cross-contamination is handled before the actual contaminated case; however, this is not always so. In this article, we review the steps involved in processing pathology specimens as they pertain to cross-contamination; share an approach covering how to troubleshoot and prevent tissue contaminants in a systematic and practical manner; present some examples from our own experiences; and compare our experience to what is reported in the literature. The information included in this article will be of use to all members of the anatomical pathology team including medical laboratory technologists, laboratory managers and supervisors, pathologist assistants, trainees in pathology, and pathologists.
组织病理学中的组织污染物并不罕见。虽然与玻璃载玻片上存在外来组织相关的问题通常很容易解决，但情况并非总是如此，并且有几个因素可能导致诊断困难。因此，在对可能的交叉污染物进行故障排除时，熟悉解剖病理学实验室中处理标本的不同步骤是必不可少的。最常见的是，在实际污染病例之前处理构成交叉污染源的标本；然而，情况并非总是如此。在本文中，我们回顾了与交叉污染相关的病理标本处理步骤；分享了一种以系统和实用的方式解决和预防组织污染物的方法；提出了一些我们自己经验的例子；并将我们的经验与文献中的报道进行了比较。本文所包含的信息将对解剖病理学团队的所有成员都有用，包括医学实验室技术员、实验室经理和主管、病理助理、病理培训生和病理学家。
