Tan Benjamin Y Q, Paliwal Prakash R, Sharma Vijay K
Department of Medicine, Division of Neurology, National University Health System, Singapore.
Department of Medicine, Yong Loo Lin School of Medicine Singapore, Singapore.
Ann Indian Acad Neurol. 2020 Mar-Apr;23(2):155-158. doi: 10.4103/aian.AIAN_483_19. Epub 2020 Feb 25.
Ischemic stroke remains a significant health problem, which is expected to increase owing to an aging population. A considerable proportion of stroke patients suffer from gastrointestinal complications, including dysphagia, gastrointestinal hemorrhage, and constipation. Often, these complications adversely affect stroke outcomes. Recent research postulates the role of "brain-gut axis" in causing gut microbiota dysbiosis and various complications and outcomes. In this review, we present our current understanding about the interaction between commensal gut microbiome and brain in determining the course of stroke.
缺血性中风仍然是一个严重的健康问题，由于人口老龄化，预计这一问题会加剧。相当一部分中风患者会出现胃肠道并发症，包括吞咽困难、胃肠道出血和便秘。这些并发症往往会对中风的预后产生不利影响。最近的研究推测“脑-肠轴”在导致肠道微生物群失调以及各种并发症和预后方面所起的作用。在这篇综述中，我们阐述了目前对于共生肠道微生物群与大脑之间的相互作用在决定中风病程方面的理解。
