Salvi Anuprita S, Patankar Sangeeta, Desai Khushal, Wankhedkar Divyesh
Department of Oral and Maxillofacial Pathology, YMT Dental College and Hospital, Navi Mumbai, Maharashtra, India.
Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Navi Mumbai, Maharashtra, India.
J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S15-S18. doi: 10.4103/jomfp.JOMFP_349_19. Epub 2020 Feb 28.
Cemento-osseous dysplasia (COD) is the most prevalent lesion and presents as an asymptomatic, mixed radiolucent/radiopaque lesion in the tooth-bearing region of the jawbones. Histological features of COD include a cellular connective tissue stroma interspersed by the islands of woven or lamellar bone and cementum-like calcifications. Radiographically, the early COD lesions appear radiolucent, whereas in the mature lesions, radiopacities are observed surrounded by a thin rim of radiolucency. Early lesions tend to get misdiagnosed as their radiographic appearance mimics periapical cyst or granuloma. In the mixed radiolucent-radiopaque stage, the lesion could be confused with chronic sclerosing osteomyelitis, cemento-ossifying fibroma, odontoma and osteoblastoma. A correct diagnosis is of utmost importance as most of the CODs are self-limiting and nonneoplastic and do not require surgical intervention. However, periodic follow-up is recommended because occasional cases of focal COD are known to progress into florid COD. Here, we present the case of focal COD in a 27-year-old male patient.
骨水泥发育异常（COD）是最常见的病变，表现为颌骨牙齿区域无症状的、透射线与阻射线混合的病变。COD的组织学特征包括细胞性结缔组织基质，其间散布着编织骨或板层骨岛以及类牙骨质钙化。在影像学上，早期COD病变表现为透射线，而在成熟病变中，可见阻射线被一薄层透射线包绕。早期病变往往会被误诊，因为其影像学表现类似根尖囊肿或肉芽肿。在透射线与阻射线混合阶段，该病变可能会与慢性硬化性骨髓炎、骨水泥化纤维瘤、牙瘤和成骨细胞瘤相混淆。正确的诊断至关重要，因为大多数COD是自限性的且为非肿瘤性，不需要手术干预。然而，建议定期随访，因为已知偶尔有局灶性COD病例会发展为 florid COD。在此，我们报告一例27岁男性患者的局灶性COD病例。
