Urs Aadithya B, Augustine Jeyaseelan, Gupta Sunita
Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Department of Oral Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
J Oral Maxillofac Pathol. 2020 Sep-Dec;24(3):576. doi: 10.4103/jomfp.JOMFP_139_20. Epub 2021 Jan 9.
Cemento-osseous dysplasia (COD) is a distinct entity, which is confined to the tooth-bearing areas of the jaws or edentulous alveolar processes.
This study analyzes the demographic, clinical, radiographic and histopathological features of COD.
Archival data from 2013 to 2017 present in the Department of Oral Pathology were retrieved. Clinicopathological and radiological features of all the cases which had been previously diagnosed as COD were analyzed in detail.
In the present study, 10 cases of COD were analyzed (1 periapical, 6 florid and 3 focal). Equal sex predilection was observed. The mean age in females and males was 42.6 years (22-64 years) and 28.6 years (17-36 years), respectively. Bony expansion was seen frequently, but pain was not a common feature. Mandible was affected almost twice as frequently as maxilla and posterior region was affected more than anterior region. Most cases showed mixed radiopaque and radiolucent lesion (5/10) and peripheral radiolucent rim (9/10) on radiographic examination. Histopathological features included the presence of curvilinear trabeculae (4/10), sheets of compact bone (3/10) or both (3/10). Foci of mineralization in form of ossicles or cementicles were noted in 5 out of 10 cases.
COD is a nonneoplastic process usually confined to the tooth-bearing areas of the jaws or edentulous alveolar processes. Depending on the location and extent, it can be either focal/periapical/florid variant. Histopathological features of COD can overlap with other fibro-osseous lesions. Hence, the correlation of clinical, radiological and histopathological features is of paramount importance in the accurate diagnosis of COD.
骨化纤维瘤（COD）是一种独特的病变，局限于颌骨的牙列区或无牙的牙槽突。
本研究分析骨化纤维瘤的人口统计学、临床、影像学和组织病理学特征。
检索口腔病理学系2013年至2017年的存档数据。对所有先前诊断为骨化纤维瘤的病例的临床病理和放射学特征进行详细分析。
在本研究中，分析了10例骨化纤维瘤病例（1例根尖型、6例 florid型和3例局灶型）。观察到性别偏好相同。女性和男性的平均年龄分别为42.6岁（22 - 64岁）和28.6岁（17 - 36岁）。经常可见骨质膨胀，但疼痛并非常见特征。下颌骨受累频率几乎是上颌骨的两倍，后部区域比前部区域受累更多。大多数病例在影像学检查中显示混合性不透光和透光病变（5/10）以及周边透光边缘（9/10）。组织病理学特征包括存在曲线形小梁（4/10）、致密骨板（3/10）或两者皆有（3/10）。10例中有5例观察到以小骨片或牙骨质小体形式存在的矿化灶。
骨化纤维瘤是一种通常局限于颌骨牙列区或无牙牙槽突的非肿瘤性病变。根据位置和范围，它可以是局灶型/根尖型/florid型变体。骨化纤维瘤的组织病理学特征可能与其他纤维 - 骨病变重叠。因此，临床、放射学和组织病理学特征的相关性对于骨化纤维瘤的准确诊断至关重要。
