• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

免疫功能正常患者的播散性隐球菌病。

Disseminated cryptococcosis in an immunocompetent patient.

作者信息

Bollam Rahul, Yassin Mohamed, Phan Tung

机构信息

Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Division of Clinical Microbiology, University of Pittsburgh and University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

出版信息

Respir Med Case Rep. 2020 Mar 3;30:101034. doi: 10.1016/j.rmcr.2020.101034. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101034
PMID:32190544
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7068684/
Abstract

Cryptococcosis is an important opportunistic infection. It is the third most common invasive fungal infection in solid organ transplant recipients. The primary organ affected is the lungs, but infection of the central nervous system and other organ systems are also seen. Here we reported a case of disseminated cryptococcosis in a healthy patient who presented with severe pneumonia, a left upper lobe nodule and enlarged mediastinal lymphadenopathy on a chest computed tomography scan.

摘要

隐球菌病是一种重要的机会性感染。它是实体器官移植受者中第三常见的侵袭性真菌感染。主要受累器官是肺,但中枢神经系统和其他器官系统的感染也可见到。在此,我们报告一例健康患者发生播散性隐球菌病的病例,该患者胸部计算机断层扫描显示有严重肺炎、左上叶结节及纵隔淋巴结肿大。

相似文献

1
Disseminated cryptococcosis in an immunocompetent patient.免疫功能正常患者的播散性隐球菌病。
Respir Med Case Rep. 2020 Mar 3;30:101034. doi: 10.1016/j.rmcr.2020.101034. eCollection 2020.
2
Disseminated Cryptococcosis in an Immunocompromised Patient with Altered Mental Status and a Lung Nodule.一名免疫功能低下、精神状态改变且有肺结节的患者发生播散性隐球菌病。
J Community Hosp Intern Med Perspect. 2023 Mar 10;13(2):34-36. doi: 10.55729/2000-9666.1157. eCollection 2023.
3
Cryptococcoma of a transplanted kidney in a patient presenting with recurrent urinary tract infection: a case report.一名反复出现尿路感染的患者移植肾隐球菌瘤:病例报告
BMC Nephrol. 2018 Apr 23;19(1):94. doi: 10.1186/s12882-018-0891-8.
4
Innate host defenses against Cryptococcus neoformans.宿主针对新型隐球菌的固有防御机制。
J Microbiol. 2016 Mar;54(3):202-11. doi: 10.1007/s12275-016-5625-7. Epub 2016 Feb 27.
5
[Disseminated cryptococcosis in an immunocompetent patient].[免疫功能正常患者的播散性隐球菌病]
J Mycol Med. 2015 Sep;25(3):208-12. doi: 10.1016/j.mycmed.2015.06.002. Epub 2015 Jul 27.
6
Orthostatic hypotension as the initial presentation of disseminated cryptococcosis in a kidney transplant recipient.直立性低血压作为肾移植受者播散性隐球菌病的首发表现。
IDCases. 2022 Jul 11;29:e01567. doi: 10.1016/j.idcr.2022.e01567. eCollection 2022.
7
Antifungal management practices and evolution of infection in organ transplant recipients with cryptococcus neoformans infection.器官移植受者新型隐球菌感染的抗真菌治疗实践与感染演变
Transplantation. 2005 Oct 27;80(8):1033-9. doi: 10.1097/01.tp.0000173774.74388.49.
8
Disseminated cryptococcosis with recurrent multiple abscesses in an immunocompetent patient: a case report and literature review.免疫功能正常患者的播散性隐球菌病伴复发性多发性脓肿:病例报告及文献复习
BMC Infect Dis. 2017 May 30;17(1):369. doi: 10.1186/s12879-017-2459-9.
9
Invasive fungal infection by Cryptococcus neoformans var. grubii with bone marrow and meningeal involvement in a HIV-infected patient: a case report.新型隐球菌变种格卢氏菌骨髓和脑膜侵犯合并 HIV 感染患者的侵袭性真菌感染:一例报告。
BMC Infect Dis. 2019 Mar 4;19(1):220. doi: 10.1186/s12879-019-3831-8.
10
Disseminated cryptococcosis manifested as a single tumor in an immunocompetent patient, similar to the cutaneous primary forms.播散性隐球菌病在免疫功能正常的患者中表现为单个肿瘤,类似于皮肤原发性形式。
An Bras Dermatol. 2016 Sep-Oct;91(5 suppl 1):29-31. doi: 10.1590/abd1806-4841.20164582.

引用本文的文献

1
A Case of Generalized Lymphadenopathy as the Initial Clinical Presentation in an Immunocompetent Patient with Disseminated Cryptococcosis.一例免疫功能正常的播散性隐球菌病患者以全身淋巴结肿大为首发临床表现的病例
Indian Dermatol Online J. 2025 Jun 17;16(4):672-674. doi: 10.4103/idoj.idoj_509_24. eCollection 2025 Jul-Aug.
2
Nanotechnology-Based Approaches for Voriconazole Delivery Applied to Invasive Fungal Infections.基于纳米技术的伏立康唑给药方法在侵袭性真菌感染中的应用
Pharmaceutics. 2023 Jan 12;15(1):266. doi: 10.3390/pharmaceutics15010266.
3
Exploring CYP51 and Its Cognate Reductase as a Drug Target.

本文引用的文献

1
The Disease Ecology, Epidemiology, Clinical Manifestations, and Management of Emerging Cryptococcus gattii Complex Infections.新型格特隐球菌复合体感染的疾病生态学、流行病学、临床表现及管理
Wilderness Environ Med. 2020 Mar;31(1):101-109. doi: 10.1016/j.wem.2019.10.004. Epub 2019 Dec 6.
2
Pathogenic Fungal Infection in the Lung.肺部病原真菌感染。
Front Immunol. 2019 Jul 3;10:1524. doi: 10.3389/fimmu.2019.01524. eCollection 2019.
3
Pulmonary cryptococcosis: A review of pathobiology and clinical aspects.肺隐球菌病:病理生物学和临床方面的综述。
探索CYP51及其同源还原酶作为药物靶点
J Fungi (Basel). 2022 Nov 28;8(12):1256. doi: 10.3390/jof8121256.
4
Identification of Disease-Associated Cryptococcal Proteins Reactive With Serum IgG From Cryptococcal Meningitis Patients.鉴定与新型隐球菌性脑膜炎患者血清 IgG 反应的疾病相关隐球菌蛋白。
Front Immunol. 2021 Jul 23;12:709695. doi: 10.3389/fimmu.2021.709695. eCollection 2021.
5
Low Glucose Mediated Fluconazole Tolerance in .低葡萄糖介导的氟康唑耐受性在……中
J Fungi (Basel). 2021 Jun 18;7(6):489. doi: 10.3390/jof7060489.
6
Disseminated cryptococcal infection in an immunocompetent patient treated with short course induction therapy.接受短程诱导治疗的免疫功能正常患者的播散性隐球菌感染
Med Mycol Case Rep. 2020 Dec 24;32:1-3. doi: 10.1016/j.mmcr.2020.12.001. eCollection 2021 Jun.
Med Mycol. 2019 Feb 1;57(2):133-150. doi: 10.1093/mmy/myy086.
4
The status of cryptococcosis in Latin America.拉丁美洲隐球菌病的现状。
Mem Inst Oswaldo Cruz. 2018;113(7):e170554. doi: 10.1590/0074-02760170554. Epub 2018 Apr 5.
5
Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis.HIV 相关隐球菌性脑膜炎的全球疾病负担:最新分析
Lancet Infect Dis. 2017 Aug;17(8):873-881. doi: 10.1016/S1473-3099(17)30243-8. Epub 2017 May 5.
6
Cryptococcosis.隐球菌病
Infect Dis Clin North Am. 2016 Mar;30(1):179-206. doi: 10.1016/j.idc.2015.10.006.
7
Cryptococcus: from environmental saprophyte to global pathogen.隐球菌:从环境腐生菌到全球病原体。
Nat Rev Microbiol. 2016 Feb;14(2):106-17. doi: 10.1038/nrmicro.2015.6. Epub 2015 Dec 21.
8
Cryptococcus gattii infections.加氏隐球菌感染
Clin Microbiol Rev. 2014 Oct;27(4):980-1024. doi: 10.1128/CMR.00126-13.
9
Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment. cryptococcosis:流行病学、真菌耐药性和新的治疗选择。
Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1377-91. doi: 10.1007/s10096-013-1915-8. Epub 2013 Jul 4.
10
Ten challenges on Cryptococcus and cryptococcosis.十项关于隐球菌和隐球菌病的挑战。
Mycopathologia. 2012 Jun;173(5-6):303-10. doi: 10.1007/s11046-011-9473-z. Epub 2011 Sep 24.