Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China.
Key Laboratory of Maricultural Organism Disease Control, Ministry of Agriculture and Rural Affairs, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China.
Viruses. 2020 Mar 17;12(3):323. doi: 10.3390/v12030323.
The family Hepeviridae includes several positive-stranded RNA viruses, which infect a wide range of mammalian species, chicken, and trout. However, few hepatitis E viruses (HEVs) have been characterized from invertebrates. In this study, a hepevirus, tentatively named Crustacea hepe-like virus 1 (CHEV1), from the economically important crustacean, the giant freshwater prawn , was characterized. The complete genome consisted of 7750 nucleotides and had a similar structure to known hepatitis E virus genomes. Phylogenetic analyses suggested it might be a novel hepe-like virus within the family Hepeviridae. To our knowledge, this is the first hepe-like virus characterized from crustaceans.
该 Hepeviridae 家族包括几种正链 RNA 病毒，可感染多种哺乳动物、鸡和鳟鱼。然而，从无脊椎动物中鉴定出的肝炎 E 病毒 (HEV) 较少。在这项研究中，从经济上重要的甲壳类动物——巨型淡水虾中鉴定出一种正肝 RNA 病毒，暂命名为甲壳类动物肝炎样病毒 1 (CHEV1)。完整基因组由 7750 个核苷酸组成，与已知的肝炎 E 病毒基因组具有相似的结构。系统进化分析表明，它可能是 Hepeviridae 家族中的一种新型肝炎样病毒。据我们所知，这是首次从甲壳类动物中鉴定出的肝炎样病毒。
